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D1411

d-Desthiobiotin

≥98% (TLC)

Synonyma:

5-Methyl-2-oxo-4-imidazolidinehexanoic acid

Přihlásit pro zobrazení organizačních a smluvních cen.

Vybrat velikost

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Velikost baleníSkladová položkaDostupnostCena
500 mg
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
4 950,00 Kč
1 g
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8 040,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C10H18N2O3
Číslo CAS:
Molekulová hmotnost:
214.26
PubChem Substance ID:
eCl@ss:
34058011
UNSPSC Code:
12352200
NACRES:
NA.25
EC Number:
208-566-2
MDL number:
Assay:
≥98% (TLC)
Form:
powder

4 950,00 Kč


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Quality Segment

assay

≥98% (TLC)

form

powder

storage temp.

2-8°C

SMILES string

C[C@@H]1NC(=O)N[C@@H]1CCCCCC(O)=O

InChI

1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1

InChI key

AUTOLBMXDDTRRT-JGVFFNPUSA-N

Application

d-Desthiobiotin has been used as a component of elution buffers:
  • to elute the precipitated proteins from the resin during coimmunoprecipitation[1]
  • to elute human Cdc45–MCM–GINS (CMG) helicase during chromatographic protein purification[2]
  • to elute the heterodimeric kinesin family member 3A/B (KIF3A/B) and kinesin associated protein 3 (KAP3)-binding APC armadillo (APCARM) domain during chromatographic purification[3]

d-Desthiobiotin is used in affinity chromatography and protein chromatography. d-Desthiobiotin can be used for protein labeling, detection and isolation.

Biochem/physiol Actions

Desthiobiotin is a non-sulfur containing biotin derivative that binds less strongly to biotin-binding proteins and is easily dislocated by biotin.[4]

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Tato položka
SML1915A557571610-M
T-26c ≥98% (HPLC)

Sigma-Aldrich

SML1915

T-26c

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

form

powder

form

powder

form

powder

form

solid


Skladovací třída

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Osvědčení o analýze (COA)

Lot/Batch Number

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Související obsah

Find protein research tools to prepare, isolate, and analyze proteins. Organized by how to extract, protect, purify, enrich, modify, and quantify proteins.


Sudha Purushothaman et al.
PloS one, 3(5), e2320-e2320 (2008-05-30)
Fatty acids are indispensable constituents of mycolic acids that impart toughness & permeability barrier to the cell envelope of M. tuberculosis. Biotin is an essential co-factor for acetyl-CoA carboxylase (ACC) the enzyme involved in the synthesis of malonyl-CoA, a committed
M Sárdy et al.
Clinical chemistry, 45(12), 2142-2149 (1999-12-10)
Tissue transglutaminase (TGc) has recently been identified as the major, if not the sole, autoantigen of gluten-sensitive enteropathy (GSE). We developed and validated an ELISA based on the human recombinant antigen and compared it to existing serological tests for GSE
S Voss et al.
Protein engineering, 10(8), 975-982 (1997-08-01)
The Strep-tag, an artificial peptide ligand of streptavidin, has gained use as an affinity handle for the purification and detection of recombinant fusion proteins. In an attempt to achieve tighter complexation of the peptide, streptavidin was engineered and the amino



Globální číslo obchodní položky

Skladová položkaGTIN
D1411-1G04061833559819
D1411-500MG04061833559826

Questions

  1. What is the recommended method for reconstituting item D1411, d-Desthiobiotin? Also, how should stock solutions be stored?

    1 answer
    1. To reconstitute item D1411, d-Desthiobiotin, use DMSO at a concentration of 62.5 mg/mL (291.70 mM). For improved solubility, warm the tube at 37 ℃ and shake it in an ultrasonic bath. The stock solution can be stored at temperatures below -20℃ for several months.

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