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Merck

Your Guide To
Protein Research

Empower Your Protein Research

Refine your protein research for optimal efficiency and reliability. Explore the potential and significance of proteins using our solutions to extract, isolate, and analyze your proteins of interest. Our diverse portfolio of solutions streamlines the entire process from protein extraction to analysis, preserving integrity and protecting against degradation throughout your workflow.

Our reliable methods empower you to unlock the full potential of your target proteins. Paired with our innovative detection tools, we deliver comprehensive insights into protein properties and functions.

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Protein Research Workflow Tools

Prepare

Prepare

Isolate

Isolate

Analyze

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Highlights

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ZooMAb<sup>®</sup> Antibodies Technology
ZooMAb® Antibodies Technology
Manufactured using our proprietary recombinant expression system, learn how ZooMAb® recombinant monoclonal antibodies are engineered and can be produced in a range of animal species, starting with rabbit.

Related Resources

Extract

Protect

  • Protease Inhibitor Cocktails

    Protease Inhibitor Cocktails maintain and preserve cellular protein composition following cell lysis. When used with CelLytics, they also preserve target protein activity. These cocktails have been optimized for a wide variety of specific applications, ensuring excellent inhibition and ease of use.

  • Phosphatase Inhibitor Cocktail

    The use of phosphatase inhibitors is critical for all types of phosphorylation studies. Compare phosphatase inhibitor cocktails to select the best one for your research.

  • ReadyShield Phosphatase and Protease Inhibitor Cocktail FAQ

    ReadyShield® phosphatase and protease inhibitor cocktail FAQ for sample protection in a variety of cell types and tissue extracts, including mammalian, plant, and microbial samples. Our ReadyShield® Protease Inhibitor Cocktail is a non-freezing solution that contains inhibitors with a broad specificity for serine, cysteine, acid proteases and aminopeptidases.

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Related Product Categories
Protein Degrader Building Blocks
Discover protein degrader building blocks for creating libraries, like PROTAC® molecules, for efficient target protein degradation in cell screenings.
Chemical Biology Tools
Our chemical biology tools incorporate techniques and strengths of chemistry to address fundamentally important research in biology, medicine, and drug discovery.
Related Applications
Cloning & Expression
Cloning, protein expression vectors and techniques for optimal gene cloning and protein expression systems.
PCR Applications
Polymerase chain reaction (PCR) is a technique for amplifying nucleic acid molecules and is commonly used in many applications, including RT-PCR, hot start PCR, end point PCR and more.
Nucleic Acid Gel Electrophoresis
Learn the basics of DNA and RNA gel electrophoresis, and how these techniques can be used to separate and purify DNA and RNA molecules based on size and charge for cloning, PCR, mass spectrometry, next generation sequencing (NGS), and Northern and Southern blotting applications.
Gel Electrophoresis
Protein gel electrophoresis is used to separate proteins for purification, characterization, and detection. Methods such as native PAGE, SDS-PAGE, 2D PAGE, and isoelectric focusing (IEF) are used in preparation for downstream applications including Western blotting, mass spectrometry, and proteomic analysis.
DNA & RNA Purification
Overview of common techniques and downstream applications for extraction and purification of genomic DNA, plasmid DNA, and total RNA from cells, tissue, blood, viruses, and other sample types.
Protein Expression
Protein expression technologies for various expression systems supporting research, therapeutics, and vaccine production.
Lysis & Protein Extraction
An overview of cell lysis and protein extraction methods including detergent solubilization, freeze-thaw lysis, osmotic shock, sonication, enzymatic cell lysis, and mechanical disruption techniques such as Dounce, Polytron, and mortar and pestle homogenization.
Protein Purification
Protein purification techniques, reagents, and protocols for purifying recombinant proteins using methods including, ion-exchange, size-exclusion, and protein affinity chromatography.
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