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L5501

L-Lysine

Name: <SC>L</SC>-Lysine
Brand: SIGMA
Price: 982 CZK

≥98% (TLC), suitable for ligand binding assays

Synonyma:

(S)-2,6-Diaminocaproic acid

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Velikost balení	Dostupnost	Cena
10 mg	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	982,00 Kč
1 g	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	2 430,00 Kč
5 g	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	2 470,00 Kč
25 g	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	6 060,00 Kč
100 g	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	14 400,00 Kč

O této položce

Lineární vzorec:

H₂N(CH₂)₄CH(NH₂)CO₂H

Číslo CAS:

56-87-1

Molekulová hmotnost:

146.19

NACRES:

NA.26

PubChem Substance ID:

24896404

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-294-2

MDL number:

MFCD00064433

Beilstein/REAXYS Number:

1722531

982,00 Kč

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Vlastnosti

Název produktu

L-Lysine, ≥98% (TLC)

Quality Level

200

assay

≥98% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

mp

215 °C (dec.) (lit.)

solubility

H₂O: soluble

SMILES string

NCCCC[C@H](N)C(O)=O

InChI

1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

InChI key

KDXKERNSBIXSRK-YFKPBYRVSA-N

Popis

General description

L-lysine contains basic side chain and is hydrophilic in nature. The N-butyl amino group in the side chain is found to be protonated at physiological pH. Upon degradation, L-lysine gives ketone bodies. Transamination of lysine with α-ketoglutarate produces acetoacetyl CoA. L-lysine serves as a precursor for secondary metabolites, such as β-lactam antibiotics. It also serves as a precursor for the biosynthesis of α-aminoadipic acid.[1]

Application

L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications. It has been used:

as a supplement in cell culture media[2][3][4][5]
as a substrate for enzymes such as L-lysine oxidase (EC 1.4.3.14)
as a component of poly-lysine polymers
as a substrate for oxidation and glycation mechanism studies
in the preparation of cobaltous lysine[6][7]

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Tato položka	62840	23128	L8021
Sigma-Aldrich L5501 L-Lysine	Sigma-Aldrich 62840 L-Lysine	Supelco 23128 L-Lysine	Sigma-Aldrich L8021 D-Lysine
form powder	form solid	form -	form powder
technique(s) ligand binding assay: suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -
assay ≥98% (TLC)	assay ≥98.0% (NT)	assay ≥95.0% (HPLC)	assay ≥98% (HPLC)
solubility H₂O: soluble	solubility H₂O: 0.1 g/mL, clear, colorless to very faintly greenish-yellow	solubility -	solubility H₂O: soluble
mp 215 °C (dec.) (lit.)	mp 215 °C (dec.) (lit.), ~215 °C (dec.)	mp 215 °C (dec.) (lit.)	mp 218 °C (dec.) (lit.)
color white to off-white	color -	color white to off-white	color white to off-white

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Skladovací třída

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Osvědčení o analýze (COA)

Lot/Batch Number

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Související obsah

Product Information Sheet - L5501

Product Information Sheet

Effect of exogenous lysine on the expression of early cephamycin C biosynthetic genes and antibiotic production in Nocardia lactamdurans MA4213.

A L Leitão et al.

Applied microbiology and biotechnology, 56(5-6), 670-675 (2001-10-17)

In beta-lactam producing microorganisms, the first step in the biosynthesis of the beta-lactam ring is the condensation of three amino acid precursors: alpha-aminoadipate, L-cysteine and D-valine. In Nocardia lactamdurans and other cephamycin-producing actinomycetes, alpha-aminoadipate is generated from L-lysine by two

Surgical and intensification procedures for defining visual pathways with cobaltous-lysine.

A D Springer et al.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 30(12), 1235-1242 (1982-12-01)

The introduction of heavy metals directly into living neuronal tissue has received little attention as a method for defining connections in the vertebrate nervous system. Procedures are described for the use of cobaltous-lysine to trace visual pathways with light microscopy.

Devlin T M

Textbook of Biochemistry: With Clinical Correlations (5th ed.), 97-97 (2002)

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Globální číslo obchodní položky

Skladová položka	GTIN
L5501-25G	04061833958162
L5501-5G	04061833958179
L5501-1G	04061833958155
L5501-100G	04061833958131
L5501-10MG	04061833958148

Questions

1–2 of 2 Questions

Anonymous

10 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  10 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

2 years ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  2 years ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
  Helpful?

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