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81709

L-Proline

≥99.5% (NT), suitable for cell culture, BioUltra

Synonyma:

(S)-Pyrrolidine-2-carboxylic acid

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Velikost baleníSkladová položkaDostupnostCena

O této položce

Empirický vzorec (Hillův zápis):
C5H9NO2
Číslo CAS:
Molekulová hmotnost:
115.13
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
205-702-2
MDL number:
Beilstein/REAXYS Number:
80810
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Název produktu

L-Proline, BioUltra, ≥99.5% (NT)

product line

BioUltra

Quality Segment

assay

≥99.5% (NT)

form

powder or crystals

optical activity

[α]20/D −85.0±1.0°, c = 5% in H2O

technique(s)

cell culture | mammalian: suitable

impurities

insoluble matter, passes filter test, ≤0.3% foreign amino acids

ign. residue

≤0.1%

loss

≤0.1% loss on drying, 20 °C (HV)

color

colorless to white

pH

6.0-7.0 (25 °C, 1 M in H2O)

mp

228 °C (dec.) (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, NH4+: ≤20 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.05, λ: 280 nm Amax: 0.05

SMILES string

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI key

ONIBWKKTOPOVIA-BYPYZUCNSA-N

Application


  • Synthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (M(pro)).: This publication discusses the synthesis of novel compounds using L-Proline and their potential as inhibitors against COVID-19, contributing to the ongoing search for effective treatments (Geedkar et al., 2024).

Other Notes

Protects enzymes against heat inactivation; Growth requirement of various microorganisms

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Tato položka
P0380P560793693
L-Proline BioUltra, ≥99.5% (NT)

Sigma-Aldrich

81709

L-Proline

L-Proline ReagentPlus®, ≥99% (HPLC)

Sigma-Aldrich

P0380

L-Proline

L-Proline from non-animal source, meets EP, USP testing specifications, suitable for cell culture

Sigma-Aldrich

P5607

L-Proline

L-Proline certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

93693

L-Proline

form

powder or crystals

form

powder

form

powder

form

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

assay

≥99.5% (NT)

assay

≥99% (HPLC)

assay

98.5-101.0% dry basis

assay

-

product line

BioUltra

product line

ReagentPlus®

product line

-

product line

TraceCERT®

optical activity

[α]20/D −85.0±1.0°, c = 5% in H2O

optical activity

-

optical activity

[α]20/D -86.0 to -84.0 °, c = 4 in water, [α]25/D -86.3 to -84.3°, c = 4 in water

optical activity

-

color

colorless to white

color

white

color

white

color

white


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Skladovací třída

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Osvědčení o analýze (COA)

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Sortimentní položky

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.






Globální číslo obchodní položky

Skladová položkaGTIN
81709-10G04061832997841
81709-100G04061832997834
81709-25G04061832997865
81709-1G-KC04061826681114

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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