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B6506

Benzamidine hydrochloride hydrate

≥99%

Synonyma:

Amidinobenzene hydrochloride, Benzamidinium chloride, Benzenecarboximidamide hydrochloride

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Vybrat velikost

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Velikost baleníSkladová položkaDostupnostCena
5 g
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
943,00 Kč
25 g
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2 640,00 Kč
100 g
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7 160,00 Kč

O této položce

Lineární vzorec:
C6H5C(=NH)NH2 · HCl · xH2O
Číslo CAS:
Molekulová hmotnost:
156.61 (anhydrous basis)
UNSPSC Code:
12352107
NACRES:
NA.77
PubChem Substance ID:
EC Number:
216-795-4
Beilstein/REAXYS Number:
3594959
MDL number:

943,00 Kč


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biological source

synthetic (organic)

Quality Level

assay

≥99%

form

powder

mp

86-88 °C (lit.)

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl[H].[H]O[H].NC(=N)c1ccccc1

InChI

1S/C7H8N2.ClH.H2O/c8-7(9)6-4-2-1-3-5-6;;/h1-5H,(H3,8,9);1H;1H2

InChI key

BQVJCMMLDJPBFZ-UHFFFAOYSA-N

Application

Benzamidine hydrochloride hydrate has been used:
  • in western blot analysis
  • in immunoprecipitation
  • in the purification of yeast dynein
  • as a protease inhibitor in the preparation of brush-border membrane vesicles
  • for the processing of human synovial fluid, blood and eye sleep
  • to prevent non-specific degradation of cartilages

Biochem/physiol Actions

Benzamidine HCl is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.

In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.
Peptidase inhibitor.

Preparation Note

Benzamidine HCl is soluble in water and alcohol. Solubility testing in water at a concentration of 50 mg/ml yields a clear solution with heating. Benzamidine HCl is sensitive to oxidation. It is recommended to prepare solutions fresh each time in degassed water prior to use. However, frozen aliquots stored under inert gas, to exclude air, may be stable for a short time. Insufficient information is available to assess the shelf-life of a frozen solution.

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Tato položka
M6500B3650434760
assay

≥99%

assay

≥98% (titration)

assay

≥99% (TLC)

assay

99%

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

form

powder

form

powder or crystals

form

powder

form

beads

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

solubility

water: 50 mg/mL, clear, colorless to light yellow

solubility

water: soluble


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Skladovací třída

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Osvědčení o analýze (COA)

Lot/Batch Number

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Contrast-enhanced CT imaging as a non-destructive tool for ex vivo examination of the biochemical content and structure of the human meniscus
Oh DJ, et al.
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society, 35(5), 1018-1028 null
Contrast-enhanced CT using a cationic contrast agent enables non-destructive assessment of the biochemical and biomechanical properties of mouse tibial plateau cartilage
Lakin BA, et al.
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society, 34(7), 1130-1138 (2016)
Sialidase unmasks mucin domain epitopes of lubricin
Solka KA, et al.
The Journal of Histochemistry and Cytochemistry, 64(11), 647-668 (2016)



Globální číslo obchodní položky

Skladová položkaGTIN
B6506-100G04061833434826
B6506-25G04061833434857
B6506-5G04061833434895

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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