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Merck
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Key Documents

07-728

Sigma-Aldrich

Anti-HRI Antibody

serum, Upstate®

Synonyma:

Anti-HCR, Anti-HRI, Anti-LEMSPAD, Anti-hHRI

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rabbit, human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... EIF2AK1(27102)
mouse ... Eif2Ak1(15467)

Specificity

HRI

Immunogen

6His-tagged fusion protein corres-ponding to residues 1-138 of mouse heme-regulated inhibitor (HRI)

Application

Detect HRI using this Anti-HRI Antibody validated for use in IP & WB.

Quality

Routinely evaluated by immunoblot on lysates from mouse reticulocytes.

Target description

72kDa

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Biochemistry, 42(21), 6536-6544 (2003-05-28)
In heme deficiency, protein synthesis is inhibited by the activation of the heme-regulated eIF2alpha kinase (HRI) through its multiple autophosphorylation. Autophosphorylation sites in HRI were identified in order to investigate their functions. We found that there were eight major tryptic
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