1491300

Oxytocin

United States Pharmacopeia (USP) Reference Standard

• Synonyma: Posterior pituitary extract, α-Hypophamine, Oxytocic hormone
• Empirický vzorec (Hillův zápis): C₄₃H₆₆N₁₂O₁₂S₂
• Číslo CAS: 50-56-6
• Molekulová hmotnost: 1007.19
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750651
• MDL number: MFCD00076731
• Beilstein/REAXYS Number: 3586108

Vlastnosti

• grade: pharmaceutical primary standard
• API family: oxytocin
• form: powder
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• SMILES string: [H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)[C@@H](C)CC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O
• InChI: 1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1
• InChI key: XNOPRXBHLZRZKH-DSZYJQQASA-N
• Gene Information: human ... OXTR(5021)

Popis

General description

Oxytocin is a nonapeptide hormone produced in the hypothalamus and secreted by the posterior pituitary. It stimulates uterine contractions and lactation. The USP reference standard enables bioassay validation, potency testing, and structural identity confirmation in oxytocin products.

The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Oxytocin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Oxytocin Injection

Biochem/physiol Actions

Stimulates uterine contraction and lactation; increases Na⁺ excretion; stimulates myometrial GTPase and phospholipase C.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable