T180
NK2 Tachykinin Receptor human
recombinant, expressed in CHO cells, membrane suspension
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About This Item
MDL number:
UNSPSC Code:
12352200
recombinant
expressed in CHO cells
Quality Level
form
membrane suspension
packaging
vial of 50 units
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... TACR2(6865)
Physical form
Supplied in 50 mM Tris-HCl, pH 7.4, containing 10% glycerol and 1% BSA. Actual concentrations and specific binding capacity are provided with each lot.
Analysis Note
Recommended assay conditions are supplied on the product data sheet. This is a bioassayed product.
Osvědčení o analýze (COA)
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X P Zeng et al.
The Journal of urology, 153(5), 1688-1692 (1995-05-01)
Functional and radioligand binding studies with selective agonists and antagonists were used to investigate tachykinin receptors in the human bladder. Strips of detrusor muscle were contracted by the tachykinins neurokinin A and neuropeptide gamma, and by the NK2 receptor selective
Daolin Tang et al.
American journal of respiratory cell and molecular biology, 41(6), 651-660 (2009-03-07)
The pathogenesis of sepsis is mediated in part by the pathogen-associated molecular pattern molecule bacterial endotoxin, which stimulates macrophages to sequentially release early (e.g., TNF-alpha, IL-1beta) and late (e.g., high-mobility group box [HMGB] 1 protein) proinflammatory mediators. The recent discovery
Y Nakajima et al.
The Journal of biological chemistry, 267(4), 2437-2442 (1992-02-05)
The mammalian tachykinin system consists of three distinct peptides, substance P, substance K, and neuromedin K, and possesses three corresponding receptors. In this investigation we examined intracellular signal transduction of the individual tachykinin receptors by transfection and stable expression of
Benjamin R Pryce et al.
Biochimica et biophysica acta. Molecular cell research, 1868(2), 118917-118917 (2020-12-02)
Duchenne's muscular dystrophy (DMD) is a severe muscle wasting disorder characterized by the loss of dystrophin expression, muscle necrosis, inflammation and fibrosis. Ongoing muscle regeneration is impaired by persistent cytokine stress, further decreasing muscle function. Patients with DMD rarely survive
Long Sun et al.
Molecular medicine reports, 17(2), 3274-3280 (2017-12-20)
The purpose of the present study was to examine the effects of myricetin on reducing cerebral ischemia injury in a rat model. A rat model of permanent middle cerebral artery occlusion (pMCAO) was used in the present study. Rats were
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