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Key Documents

O7139

Sigma-Aldrich

Monoclonal Anti-Oligodendrocyte Marker O4 antibody produced in mouse

clone O4, purified immunoglobulin, lyophilized powder

Synonyma:

Oligodendrocyte Marker O4 Antibody

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

O4, monoclonal

form

lyophilized powder

species reactivity

mouse, rat, chicken, human

technique(s)

flow cytometry: 0.25 μg/106 cells (rate differentiated cortical stem cells)
immunocytochemistry: 1-10 μg/mL

isotype

IgM

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... OMG(4974)

General description

Monoclonal anti-oligodendrocyte marker O4 was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with white matter of the corpus callosum from bovine brain. Oligodendrocytes are myelinating cells in the central nervous system (CNS) that form the myelin sheath of axons to support rapid nerve conduction.

Immunogen

white matter of corpus callosum from bovine brain.

Application

Monoclonal anti-oligodendrocyte marker O4 antibody produced in mouse has been used in immunocytochemistry and immunofluorescence.

Biochem/physiol Actions

Oligodendrocyte marker O4 functions as a development marker of oligodendrocytes. The monoclonal anti-oligodendrocyte marker O4 antibody has been used to describe a biologically distinct stage of the oligodendroglial lineage in-vitro.†

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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Oligodendrocytes: biology and pathology
Bradl M, et al.
Acta Neuropathologica, 119, 37-53 (2010)
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Oncotarget, 8(12), 19855-19865 (2017-04-21)
Neural stem/progenitor cells (NSPCs) are an important source of cells for cell replacement therapy after nerve injury. How to induce NSPCs differentiation towards neurons and oligodendrocytes is a challenging issue in neuroscience research. In the present study, we polarized microglia

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