M0689
Myelin Basic Protein Antigen from human brain
≥95% (SDS-PAGE)
Synonyma:
Myelin Antigen, Myelin Basic Protein
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| Velikost balení | Skladová položka | Dostupnost | Cena |
|---|---|---|---|
| 1 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 17 800,00 Kč |
O této položce
Form:
lyophilized powder
Assay:
≥95% (SDS-PAGE)
Biological source:
human brain
17 800,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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Dovolte nám, abychom vám pomohliGeneral description
Myelin basic protein (MBP) is an 18.5kDa protein encoded by the gene mapped to human chromosome 18q22qter. MBP is a major component of myelin sheath and is highly expressed in central nervous system (CNS).
Application
Myelin basic protein antigen from human brain has been used in enzyme-linked immunosorbent spot assays.
Biochem/physiol Actions
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP function as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). It also has a crucial role to play in human demyelinating diseases including multiple sclerosis (MS). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis.
Determined using polyclonal and monoclonal antibodies against MBP.
Physical form
Lyophilized from 10mM HCl.
Other Notes
Blood samples from donors were tested and found to be negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV.
1 of 1
Tato položka | |||
|---|---|---|---|
| biological source human brain | biological source human | biological source bovine | biological source - |
| assay ≥95% (SDS-PAGE) | assay ≥65% (SDS-PAGE) | assay ≥90% (SDS-PAGE) | assay ≥95% (HPLC) |
| technique(s) ELISA: suitable | technique(s) - | technique(s) activity assay: suitable | technique(s) - |
| form lyophilized powder | form buffered aqueous glycerol solution | form lyophilized powder | form lyophilized |
| storage temp. −20°C | storage temp. −70°C | storage temp. −20°C | storage temp. −20°C |
| Gene Information human ... MBP(4155) | Gene Information human ... MBP(4155) | Gene Information cow ... MBP(618684) | Gene Information - |
Skladovací třída
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
Distinct T cell signatures define subsets of patients with multiple sclerosis.
Johnson MC
Neurology? neuroimmunology & neuroinflammation, 3(5), e278-e278 (2016)
Localization of the human myelin basic protein gene (MBP) to region 18q22----qter by in situ hybridization.
Saxe DF
Cytogenetics and Cell Genetics, 39(4), 246-249 (1985)
MyelStones: the executive roles of myelin basic protein in myelin assembly and destabilization in multiple sclerosis.
Vassall KA
The Biochemical Journal, 472(1), 17-32 (2015)
Globální číslo obchodní položky
| Skladová položka | GTIN |
|---|---|
| M0689-1MG | 04061834037354 |