This material is only slightly soluble in water at a reported rate of 11.7 mg/L. The solubility of this product is tested in DMSO at a minimum rate of 20 mg/mL, with most lots soluble at 40 mg/mL. Other reported solvents include chloroform, ethanol, methanol and n-propanol. Following solubilization in any of the solvents listed above, stock solutions may typically be diluted with aqueous solvents or buffers.
F1293
Finasteride
≥98% (HPLC), Selective 5α-reductase inhibitor, powder
Synonyma:
N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, N-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamide, MK-906
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| Velikost balení | Skladová položka | Dostupnost | Cena |
|---|---|---|---|
| 100 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 2 850,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C23H36N2O2
Číslo CAS:
Molekulová hmotnost:
372.54
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
2 850,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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Dovolte nám, abychom vám pomohliNázev produktu
Finasteride, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: soluble >20 mg/mL
storage temp.
room temp
SMILES string
[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)C=CC(=O)N2
InChI
1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
InChI key
DBEPLOCGEIEOCV-WSBQPABSSA-N
Gene Information
human ... HSD3B1(3283), SRD5A1(6715), SRD5A2(6716)
rat ... Hsd3b1(360348), Srd5a1(24950), Srd5a2(64677)
Application
Finasteride has been used:
- as a component of L-15 media to investigate the effects of finasteride exposure on brain, liver and testis tissues[1]
- in culture medium to treat tumor cells in vitro[2]
- as a positive control to treat benign prostatic hyperplasia (BPH)
- to examine its effect on structural and molecular biology on the ventral prostate of senile mice[3]
Biochem/physiol Actions
Finasteride can reduce serum and scalp dihydrotestosterone (DHT) by preventing the transformation of testosterone to DHT. It is usually used to manage benign prostate hyperplasia and pattern hair loss in male. Finasteride possesses androgen-distracting properties.[1]
Selective 5α-reductase inhibitor; antiandrogen.
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Tato položka | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - |
| form powder | form powder | form powder | form - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. room temp | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: soluble >20 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility DMSO: ≥15 | solubility - |
| color white to beige | color white to beige | color white to tan | color - |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 1B
Skladovací třída
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Globální číslo obchodní položky
| Skladová položka | GTIN |
|---|---|
| F1293-100MG | 04061833611845 |
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Is this product soluble in distilled water? I need this information because I am planning a scientific experiment.
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