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E4250

(−)-Epinephrine

≥99% (HPLC), powder, adrenoceptor agonist

Synonyma:

(−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine

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Velikost baleníSkladová položkaDostupnostCena
1 g
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1 230,00 Kč
5 g
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2 460,00 Kč
10 g
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4 560,00 Kč

O této položce

Lineární vzorec:
(HO)2C6H3CH(OH)CH2NHCH3
Číslo CAS:
Molekulová hmotnost:
183.20
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-098-7
MDL number:
Beilstein/REAXYS Number:
2368277
Quality level:

1 230,00 Kč


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Název produktu

(−)-Epinephrine,

Quality Level

mp

215 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChI key

UCTWMZQNUQWSLP-VIFPVBQESA-N

Biochem/physiol Actions

Adrenoceptor agonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and β-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50 mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.

Porovnat podobné položky

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1 of 1

Tato položka
E4375I6504324900
Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

mp

215 °C (dec.) (lit.)

mp

-

mp

175 °C (dec.) (lit.)

mp

-

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)
rat ... Adra1a(29412), Adra2a(25083), Adrb1(24925), Adrb2(24176), Drd1a(24316), Drd2(24318)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)

Gene Information

human ... ADRB2(154)

Gene Information

-


pictograms

Skull and crossbones

signalword

Danger

Skladovací třída

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

hcodes

Hazard Classifications

Acute Tox. 2 Dermal



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Globální číslo obchodní položky

Skladová položkaGTIN
E4250-10G04061835253203
E4250-5G04061835259632
E4250-1G04061835253210

Questions

1–2 of 2 Questions  
  1. When this product is reconstituted in DMSO, at what temperature should it be stored?

    1 answer
    1. The stability of this product when prepared in DMSO has not been determined. In general, solutions in DMSO should be prepared fresh and used promptly. Epinephrine is most stable in acidic aqueous solutions at pH 3.6, when stored tightly sealed under nitrogen or argon. Solutions prepared in basic buffers are unstable and turn red in color due to degradation. Published literature indicates solutions are stable for at least 1 month when stored at 4°C or 25°C. Commercial solutions are often assigned a shelf life of greater than 1 year.

      Helpful?

  2. Hi, Is it possible to reconstitute the epinephrine solution in something less aggressive than 0.5 M HCl ? Sincerely, Alex

    1 answer
    1. This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.

      Helpful?

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