The product is freely soluble in water (~50 mg/mL).
C4520
Cephalothin sodium salt
Synonyma:
7-(2-Thienylacetamido)cephalosporanic acid sodium salt, Cephalotin sodium salt
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Vybrat velikost
Změnit zobrazení
| Velikost balení | Skladová položka | Dostupnost | Cena |
|---|---|---|---|
| 250 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 1 600,00 Kč | |
| 1 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 3 610,00 Kč | |
| 5 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 12 300,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C16H15N2NaO6S2
Číslo CAS:
Molekulová hmotnost:
418.42
UNSPSC Code:
51282506
NACRES:
NA.85
PubChem Substance ID:
EC Number:
200-394-6
Beilstein/REAXYS Number:
4120706
MDL number:
1 600,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohliform
crystalline powder
Quality Level
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C([O-])=O
InChI
1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1
InChI key
VUFGUVLLDPOSBC-XRZFDKQNSA-M
General description
Chemical structure: β-lactam
Application
Cephalothin is a first-generation cephalosporin antibiotic used to study the mechanism of liposome encapsulated antibiotics[1], strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics[2], and for immunology studies in relation to antibiotics.[3] It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Mode of Action: Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.
Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.
Mode of Resistance: Production of cephalosporinase will inactivate the product.
Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.
Mode of Resistance: Production of cephalosporinase will inactivate the product.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
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Tato položka | |||
|---|---|---|---|
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form crystalline powder | form powder | form powder | form powder or crystals |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes |
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Skladovací třída
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
J V Desiderio et al.
The Journal of infectious diseases, 148(3), 563-570 (1983-09-01)
Multilamellar liposomes (lipid bilayer vesicles) composed of phosphatidylcholine, cholesterol, and phosphatidylserine (molar ratio, 6:3:1) were produced and then made to entrap an aqueous solution of cephalothin. Resident murine peritoneal macrophages were shown to be capable of interiorizing the liposome-antibiotic complex;
Min-Kyung Kang et al.
Dental materials journal, 31(1), 98-105 (2012-01-27)
Dental implant failure often occurs due to oral bacterial infection. The aim of this study was to demonstrate that antibiotic efficacy could be enhanced with modified titanium. First, the titanium was modified by anodization and heat-treatment. Then, a biomimetic coating
Angela Gomes de Vasconcellos et al.
Japanese journal of infectious diseases, 65(1), 7-12 (2012-01-26)
Cellulitis is an important cause of hospitalization in pediatrics. Because Staphylococcus aureus is the main pathogen of cellulitis, medicinal therapeutics should take the changing resistance profile of this organism into consideration. The aim of this study was to evaluate the
Globální číslo obchodní položky
| Skladová položka | GTIN |
|---|---|
| C4520-250MG | 04061834373926 |
| C4520-100MG | 04061833492277 |
| C4520-5G | 04061834402077 |
| C4520-1G | 04061833492284 |
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What is the solubility of Cephalothin sodium salt product C4520?
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