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C3394

Cordycepin

Name: Cordycepin
Brand: SIGMA
Price: 3610 CZK

from Cordyceps militaris, ≥98% (HPLC), powder, adenosine analogue

Synonyma:

3′-Deoxyadenosine

Přihlásit pro zobrazení organizačních a smluvních cen.

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Velikost balení	Dostupnost	Cena
10 mg	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	3 610,00 Kč
25 mg	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	8 930,00 Kč
100 mg	Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.	21 400,00 Kč

O této položce

Empirický vzorec (Hillův zápis):

C₁₀H₁₃N₅O₃

Číslo CAS:

73-03-0

Molekulová hmotnost:

251.24

NACRES:

NA.77

PubChem Substance ID:

24892611

UNSPSC Code:

12352200

EC Number:

200-791-4

MDL number:

MFCD00037998

Beilstein/REAXYS Number:

35194

Form:

powder

Quality level:

200

3 610,00 Kč

Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.

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Vlastnosti

Název produktu

Cordycepin, from Cordyceps militaris

biological source

Cordyceps militaris

Quality Level

200

form

powder

antibiotic activity spectrum

fungi

mode of action

DNA synthesis | interferes, enzyme | inhibits

storage temp.

−20°C

SMILES string

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)C[C@H]3O

InChI

1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1

InChI key

OFEZSBMBBKLLBJ-BAJZRUMYSA-N

Gene Information

rat ... Adora1(29290)

Popis

General description

Chemical structure: nucleoside

Biochem/physiol Actions

Cordycepin is an adenosine analogue that is readily converted to cordycepin 5′-triphosphate; can be used for 3′-end labeling of RNA.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide and Gene Regulation research. Discover more featured Cyclic Nucleotide and Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Porovnat podobné položky

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Zobrazit rozdíly

1 of 1

Tato položka	T0642	PHL82505	G2536
Sigma-Aldrich C3394 Cordycepin	Sigma-Aldrich T0642 Tubercidin	PHL82505 Cordycepin	Sigma-Aldrich G2536 Ganciclovir
form powder	form powder	form -	form powder
Quality Level 200	Quality Level 200	Quality Level -	Quality Level 300
storage temp. −20°C	storage temp. -	storage temp. 2-8°C	storage temp. 2-8°C
Gene Information rat ... Adora1(29290)	Gene Information rat ... Adora1(29290)	Gene Information -	Gene Information -
biological source Cordyceps militaris	biological source Streptomyces tubercidicus	biological source -	biological source -
antibiotic activity spectrum fungi	antibiotic activity spectrum fungi, parasites, viruses	antibiotic activity spectrum -	antibiotic activity spectrum viruses

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pictograms

GHS06

signalword

Danger

hcodes

H301 + H311 + H331

pcodes

P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Skladovací třída

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number

0000488199

0000467763

0000455818

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Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

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Sortimentní položky

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Discover Bioactive Molecules for Nucleotides

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

Související obsah

Product Information Sheet - C3394

Product Information Sheet

Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells.

E N Kodama et al.

Biochemical pharmacology, 59(3), 273-281 (1999-12-28)

The nucleoside analogue cordycepin (3'-deoxyadenosine, 3'-dA) is substantially more cytotoxic to terminal deoxynucleotidyl transferase positive (TdT+) leukemic cells than to TdT leukemic cells in vitro in the presence of an adenosine deaminase inhibitor, deoxycoformycin (dCF), and has been considered as

Cordycepin (3'-deoxyadenosine) attenuates age-related oxidative stress and ameliorates antioxidant capacity in rats.

Thiyagarajan Ramesh et al.

Experimental gerontology, 47(12), 979-987 (2012-09-25)

Free radical-induced oxidative damage is considered to be the most important consequence of the aging process. The activities and capacities of antioxidant systems of cells decline with increased age, leading to the gradual loss of pro-oxidant/antioxidant balance and resulting in

mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end.

Wei Su et al.

RNA (New York, N.Y.), 19(1), 1-16 (2012-11-29)

Metazoan replication-dependent histone mRNAs are only present in S-phase, due partly to changes in their stability. These mRNAs end in a unique stem-loop (SL) that is required for both translation and cell-cycle regulation. Previous studies showed that histone mRNA degradation

Zobrazit všechny související dokumenty

Globální číslo obchodní položky

Skladová položka	GTIN
C3394-100MG	04061833269787
C3394-10MG	04061835555925
C3394-25MG	04061833485767

Questions

10 months ago

C3394의 cordycepin 농도는 몇 ppm입니까? 혹시 성적서도 볼수 있을까요?

1 answer
1. Technical Support
  
  10 months ago
  
  This product is in powder form and has a minimum purity of 98%. The purity is lot-specific and reported in the Certificate of Analysis. Please see the link below to review a sample or lot-specific Certificate:
  https://www.sigmaaldrich.com/product/sigma/c3394#product-documentation
  Please see the link below to review additional information available in the product datasheet:
  https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/325/006/c3394pis.pdf
  
  Helpful?

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