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B6768

Sigma-Aldrich

Boric acid

BioReagent, for molecular biology, suitable for cell culture, suitable for plant cell culture, ≥99.5%

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About This Item

Lineární vzorec:
H3BO3
Číslo CAS:
10043-35-3
Molekulová hmotnost:
61.83
EC Number:
233-139-2
MDL number:
MFCD00011337
UNSPSC Code:
12161700
eCl@ss:
38120104
PubChem Substance ID:
24891821
NACRES:
NA.25

grade

for molecular biology

Quality Level

200

vapor pressure

2.6 mmHg ( 20 °C)

product line

BioReagent

assay

≥99.5%

form

powder

technique(s)

cell culture | mammalian: suitable
cell culture | plant: suitable

pH

5.1 (25 °C, 1.8 g/L)

mp

160 °C (dec.) (lit.)

solubility

water: 40 mg/mL, clear, colorless

density

1.49 g/cm3 at 23 °C

cation traces

Fe: ≤5 ppm
Mg: ≤5 ppm
heavy metals (as Pb): ≤10 ppm

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

foreign activity

DNase, RNase, and protease, none detected

storage temp.

room temp

SMILES string

OB(O)O

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChI key

KGBXLFKZBHKPEV-UHFFFAOYSA-N

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Související kategorie

General description

Boric acid is a weak monobasic Lewis acid (electron pair acceptor), which reacts reversibly with alcohols. It is used in dermal and women′s hygiene products due to its mild antibacterial and antifungal effects. Boric acid is used as a buffer in ophthalmic products. It acts as an effective solid lubrication agent because of its molecular structure. Boric acid finds its applications in glass making, fire retardant. Boric acid is used in biochemistry in buffer solutions. It also forms complex equilibria in solution, with the tetraborate ion (B4O7 2- ) being the predominant species. Borate buffers are involved in discontinuous electrophoresis and capillary electrophoresis systems for the separation of proteins and nucleic acids.

Application

Boric acid has been used:
  • to prepare boric buffer for the quantification of primary amine groups at the surface of nanocapsules
  • to study its effects on epigenetic change
  • for the estimation of protein in wheatgrass using Kjeldahl method

Used to promote amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents.
Intensified Azeotropic Distillation: A Strategy for Optimizing Direct Amidation

Features and Benefits

  • Environment-friendly
  • Non-toxic 

Pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Osvědčení o analýze (COA)

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Supelco

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Sigma-Aldrich

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Boric acid

Joy E Kirkpatrick et al.
Epigenetics, 13(5), 557-572 (2018-06-22)
Periodontal disease (PD) afflicts 46% of Americans with no effective adjunctive therapies available. While most pharmacotherapy for PD targets bacteria, the host immune response is responsible for driving tissue damage and bone loss in severe disease. Herein, we establish that
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Cell metabolism, 32(4), 561-574 (2020-10-08)
Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing systemic redox homeostasis have had limited success. A noninvasive, sustained approach would enable the long-term control of redox signaling for
C A Yoder et al.
Poultry science, 85(7), 1285-1293 (2006-07-13)
Nicarbazin (NCZ) is an anticoccidial drug routinely used in the poultry industry that can negatively affect reproduction by reducing egg production, egg weight, and egg hatchability. The molecular mechanisms by which NCZ affects reproduction are unknown. Lipoprotein lipase, vitellogenin, transglutaminase
Lisa M Røst et al.
Metabolites, 10(2) (2020-02-26)
Absolute quantification of intracellular metabolite pools is a prerequisite for modeling and in-depth biological interpretation of metabolomics data. It is the final step of an elaborate metabolomics workflow, with challenges associated with all steps-from sampling to quantifying the physicochemically diverse
Akie Shimotohno et al.
Plant & cell physiology, 56(4), 620-630 (2015-02-12)
Boron, an essential micronutrient, is transported in roots of Arabidopsis thaliana mainly by two different types of transporters, BORs and NIPs (nodulin26-like intrinsic proteins). Both are plasma membrane localized, but have distinct transport properties and patterns of cell type-specific accumulation
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