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E3876

N-Ethylmaleimide

crystalline, ≥98% (HPLC)

Synonyma:

NEM

Přihlásit pro zobrazení organizačních a smluvních cen.

Vybrat velikost

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Velikost baleníSkladová položkaDostupnostCena
5 g
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3 410,00 Kč
25 g
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12 000,00 Kč
100 g
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32 600,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C6H7NO2
Číslo CAS:
128-53-0
Molekulová hmotnost:
125.13
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
24278420
EC Number:
204-892-4
Beilstein/REAXYS Number:
112448
MDL number:
MFCD00005509

3 410,00 Kč

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biological source

synthetic (organic)

Quality Level

200

assay

≥98% (HPLC)

form

crystalline

storage condition

(Tightly closed. Dry. Keep in a well-ventilated place. )

technique(s)

activity assay: suitable, co-immunoprecipitation (co-IP): suitable, immunoblotting: suitable

color

white to faint yellow

bp

210 °C (lit.)

mp

43-46 °C (lit.)

solubility

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faint yellow or tan

suitability

suitable for Western blot

application(s)

life science and biopharma

storage temp.

2-8°C

SMILES string

CCN1C(=O)C=CC1=O

InChI

1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

InChI key

HDFGOPSGAURCEO-UHFFFAOYSA-N

Gene Information

human ... KCNQ2(3785), KCNQ4(9132), KCNQ5(56479), SLC6A3(6531), SLC6A4(6532)

Application

Reagent for the covalent modification of cysteine residues in proteins.

Biochem/physiol Actions

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.
Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

Preparation Note

NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and significantly dependent on pH.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

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Tato položka
E1271C13408WH0056479M1
N-Ethylmaleimide crystalline, ≥98% (HPLC)

Sigma-Aldrich

E3876

N-Ethylmaleimide

N-Ethylmaleimide BioXtra, ≥98% (HPLC)

Sigma-Aldrich

E1271

N-Ethylmaleimide

O-(Carboxymethyl)hydroxylamine hemihydrochloride 98%

Sigma-Aldrich

C13408

O-(Carboxymethyl)hydroxylamine hemihydrochloride

Monoclonal Anti-KCNQ5 antibody produced in mouse clone 2E2, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

WH0056479M1

Monoclonal Anti-KCNQ5 antibody produced in mouse

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

98%

assay

-

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic)

biological source

mouse

Gene Information

human ... KCNQ2(3785), KCNQ4(9132), KCNQ5(56479), SLC6A3(6531), SLC6A4(6532)

Gene Information

human ... SLC6A3(6531), SLC6A4(6532)

Gene Information

-

Gene Information

human ... KCNQ5(56479)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

crystalline

form

-

form

crystalline powder, powder or crystals

form

buffered aqueous solution

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

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pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Skladovací třída

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

163.2 °F - closed cup

flash_point_c

72.9 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number
0000561658
0000557120
0000552192
0000552193
0000548922

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Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

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Globální číslo obchodní položky

Skladová položkaGTIN
E3876-5G04061835518098
E3876-25G04061835544417
E3876-100G04061833603437

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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