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Merck

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MAB1307

Mouse Anti-Human IgG1 Antibody, clone HP6001, Fc

clone HP6001, Chemicon®, from mouse

Synonyma:

Anti-CD32, Anti-FCG2, Anti-FCGR2, Anti-FCGR2C, Anti-FcGRIIB, Anti-FcRII-c, Anti-FcgammaRIIb, Anti-IGFR2

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Vybrat velikost

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Velikost baleníSkladová položkaDostupnostCena
500 μg

Očekávané datum odeslání18. května 2026odAreál Kühne+Nagel spol. s r.o.

6 210,00 Kč

O této položce

UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
HP6001, monoclonal
Application:
ELISA, RIA, WB
Citations:
8

6 210,00 Kč


Očekávané datum odeslání18. května 2026podrobné informace


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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

secondary antibodies

clone

HP6001, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, radioimmunoassay: suitable, western blot: suitable

isotype

IgG2b

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FCGR2B(2213)

Immunogen

Epitope: Fc fragment

Application

Detect Human IgG1 using this Mouse anti-Human IgG1 Antibody, clone HP6001, Fc validated for use in ELISA, RIA & WB.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
This antibody employed as both a capture antibody and a detection antibody for human IgG1 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Human IgG1 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1- 100% human IgG subclass 2- 0.25% human IgG subclass 3- 0.01%

human IgG subclass 4-0.01% Isoelectric Focusing: mean pI 8.0

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02 M Phosphate buffer, 0.25 M NaCl containing 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MABN1055

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tato položka
MAB1308MAB1302MAB1312
conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

technique(s)

ELISA: suitable, western blot: suitable, radioimmunoassay: suitable

technique(s)

ELISA: suitable, radioimmunoassay: suitable, western blot: suitable

technique(s)

ELISA: suitable, radioimmunoassay: suitable, western blot: suitable

technique(s)

ELISA: suitable, radioimmunoassay: suitable, western blot: suitable

clone

HP6001, monoclonal

clone

HP6002, monoclonal

clone

HP6017, monoclonal

clone

HP6023, monoclonal


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Skladovací třída

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity.
Tian, et al.
Nature cancer, 3, 1318-1335 (2023)
Lei Tian et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 28(1), 201-214 (2021-10-15)
mAbs blocking immune checkpoints have emerged as important cancer therapeutics, as exemplified by systemic administration of the IgG1 anti-CD47 mAb that blocks the "don't eat me" pathway. However, this strategy is associated with severe toxicity. To improve therapeutic efficacy while
Bo Xu et al.
Nature communications, 12(1), 5908-5908 (2021-10-10)
Oncolytic herpes simplex virus-1 is capable of lysing tumor cells while alerting the immune system. CD47, in collaboration with SIRPα, represents an important immune checkpoint to inhibit phagocytosis by innate immune cells. Here we show locoregional control of glioblastoma by



Globální číslo obchodní položky

Skladová položkaGTIN
MAB130704053252578007

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