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Phosphoryl chloride

for synthesis

Synonyma:

Phosphoryl chloride, Phosphorus oxide trichloride, Phosphorus oxychloride

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Velikost baleníSkladová položkaDostupnostCena
250 mL
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1 580,00 Kč
1 L
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3 610,00 Kč
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298 800,00 Kč

O této položce

Číslo CAS:
Molekulová hmotnost:
153.33
UNSPSC Code:
12352101
EC Index Number:
233-046-7
NACRES:
NA.22
MDL number:
Assay:
≥99.0% (argenometric)
Grade:
synthesis grade
Bp:
105.3 °C/1013 hPa
Vapor pressure:
36 hPa ( 20 °C)

1 580,00 Kč


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grade

synthesis grade

Quality Segment

vapor pressure

36 hPa ( 20 °C)

assay

≥99.0% (argenometric)

form

liquid

potency

36 mg/kg LD50, oral (Rat)

dilution

(for synthesis)

pH

1.0 (25 °C, 5 g/L in H2O)

bp

105.3 °C/1013 hPa

mp

1-2 °C

density

1.68 g/cm3 at 20 °C (DIN 51757)

storage temp.

2-30°C

SMILES string

[P](=O)(Cl)(Cl)Cl

InChI

1S/Cl3OP/c1-5(2,3)4

InChI key

XHXFXVLFKHQFAL-UHFFFAOYSA-N

General description

for synthesis

Application

Phosphoryl chloride is a strong Lewis acid that can be used as:
  • A phosphorylating agent for the selective phosphorylation of alcohols, amines, and thiols.
  • A dehydrating agent for alcohols, amides, and cyanohydrins.
  • A reagent to synthesize Vilsmeier reagent for Vilsmeier-Haack formylation reactions.
  • A chlorinating agent for the chlorination of heterocyclic compounds.
  • A reagent to prepare dihydroisoquinolines and isoquinolines by cyclization of N-β-phenylethyl amides via Bischler-Napieralski reaction.

Analysis Note

Assay (argentometric)≥ 99.0 %Density (d 20 °C/ 4 °C)1.673 - 1.677Identity (IR)passes test

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Tato položka
201170262099381829
grade

synthesis grade

grade

-

grade

-

grade

-

assay

≥99.0% (argenometric)

assay

99%

assay

99.999%

assay

97%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

liquid

form

liquid

form

liquid

form

-

vapor pressure

36 hPa ( 20 °C)

vapor pressure

104 mmHg ( 50 °C), 28 mmHg ( 20 °C)

vapor pressure

104 mmHg ( 50 °C), 28 mmHg ( 20 °C)

vapor pressure

-

mp

1-2 °C

mp

1.25 °C (lit.)

mp

1.25 °C (lit.)

mp

-


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signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1 - STOT RE 1 Inhalation

target_organs

Respiratory Tract

supp_hazards

Skladovací třída

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable



Osvědčení o analýze (COA)

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Synthesis and chemical transformations of mono-and disubstituted cyanamides
Nekrasov DD
Russ. J. Org. Chem., 40(10) (2004)
Phosphorus Oxychloride
Meier MS, et al.
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)



Globální číslo obchodní položky

Skladová položkaGTIN
822339100004022536489766
822339025004022536489759

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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