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14462

(−)-α-Bisabolol

≥93% (GC)

Synonyma:

(-)-alpha-Bisabolol, (−)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, Levomenol

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Vybrat velikost

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Vám/Skladová položkaDostupnostCena
5 mL
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1 710,00 Kč
25 mL
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4 470,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C15H26O
Číslo CAS:
Molekulová hmotnost:
222.37
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
208-205-9
MDL number:
Assay:
≥93% (GC)

1 710,00 Kč


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Quality Segment

assay

≥93% (GC)

optical activity

[α]/D -58±5°, neat

refractive index

n20/D 1.496

functional group

hydroxyl

SMILES string

C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1

InChI

1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1

InChI key

RGZSQWQPBWRIAQ-CABCVRRESA-N

General description

(-)-α-Bisabolol is the major constituent of essential oil from leaves of Hymenocrater yazdianus[1].

Application

(-)-α-Bisabolol was used to investigate the leishmanicidal and cytotoxic activity of essential oil of Vanillosmopsis arborea[2].

Biochem/physiol Actions

α-Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias[3]. It is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat[4]. It also inhibits human and rat glioma cell growth and survival[1]. It is a potential new therapeutic agent against leishmaniasis[2].

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Tato položka
95426PHL80005W466620
(−)-α-Bisabolol phyproof® Reference Substance

PHL80005

(−)-α-Bisabolol

assay

≥93% (GC)

assay

≥93% (GC)

assay

≥90.0% (GC)

assay

≥95%

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

300

refractive index

n20/D 1.496

refractive index

-

refractive index

-

refractive index

-

functional group

hydroxyl

functional group

-

functional group

-

functional group

-

optical activity

[α]/D -58±5°, neat

optical activity

[α]/D -60±2°, neat

optical activity

-

optical activity

-


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hcodes

Hazard Classifications

Aquatic Chronic 3

Skladovací třída

10 - Combustible liquids

flash_point_f

289.4 °F - closed cup

flash_point_c

143 °C - closed cup

ppe

Eyeshields, Gloves



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Osvědčení o analýze (COA)

Lot/Batch Number

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Questions

1–4 of 4 Questions  
  1. Could you please provide the specific optical rotation α α_D (with conditions and solvent) for the (–)-α-bisabolol enantiomer for this batch?

    1 answer
    1. The range for specific optical rotation for this product is -63.0 to -53.0 degrees and is determined with a neat sample at 20 °C. The lot-specific value can be found in the Certificate of Analysis (COA).

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. Is the product α-Bisabolol (catalog number 14462-5ML) synthetic or naturally sourced?

    1 answer
    1. The source of this material may change from lot to lot. Historically, both plant sourced and synthetically derived material have been available.

      Helpful?

  4. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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