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Merck

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C8261

Sodium chenodeoxycholate

≥97%

Sinônimo(s):

3α,7α-Dihydroxy-5β-cholanic acid, 5β-Cholanic acid-3α,7α-diol, Chenodeoxycholic acid sodium salt, Chenodesoxycholic acid, Chenodiol

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Sobre este item

Fórmula empírica (Notação de Hill):
C24H39NaO4
Número CAS:
Peso molecular:
414.55
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
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description

anionic

Quality Segment

assay

≥97%

form

powder

mol wt

414.55 g/mol

technique(s)

protein purification: suitable

SMILES string

[Na].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])CC[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O4.Na.H/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);;/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;;/m1../s1

InChI key

WANBNZVOEKGHSS-VQNKLXGESA-N

General description

Sodium chenodeoxycholate is a bile salt, which has been shown to accelerate colonic transit and improve bowel function. [1]

Application

Sodium chenodeoxycholate has been used in a study to assess DNA repair response in the bacterium Escherichia coli. [2] It has also been used in a study to investigate the physical and chemical factors influencing germination of Clostridium difficile spores. [3]

Biochem/physiol Actions

Bile Salt

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Este Item
30970C644527029
form

powder

form

powder

form

powder

form

powder

assay

≥97%

assay

≥98.0% (dry matter, NT)

assay

≥99%

assay

≥97.0% (dried material, NT)

technique(s)

protein purification: suitable

technique(s)

DNA purification: suitable, RNA purification: suitable, electrophoresis: suitable

technique(s)

-

technique(s)

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

description

anionic

description

anionic

description

anionic

description

anionic

mol wt

414.55 g/mol

mol wt

micellar avg mol wt 1200-5000

mol wt

micellar avg mol wt 900-1300

mol wt

micellar avg mol wt 900-1300


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Repr. 2

Classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



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Artigos

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.


L J Wheeldon et al.
Journal of applied microbiology, 105(6), 2223-2230 (2009-01-06)
To investigate the influence of chemical and physical factors on the rate and extent of germination of Clostridium difficile spores. Germination of C. difficile spores following exposure to chemical and physical germinants was measured by loss of either heat or
Maricella K Gomez et al.
Journal of food science, 83(6), 1569-1578 (2018-05-29)
Dandelion (Taraxacum officinale) var. Garnet Stem was harvested from Texas and New Jersey for identification, quantification of phytochemicals, measurement of free radical scavenging activity, and bile acid binding capacity. The red midrib and petioles were extracted with methanol or ethanol
Tina Kauss et al.
Journal of pharmaceutical sciences, 108(8), 2805-2813 (2019-03-18)
Current pediatric antibiotic therapies often use oral and parenteral routes of administration. Neither are suitable for treating very sick neonates who cannot take oral medication and may be several hours away from hospital in developing countries. Here, we report on



Número de item de comércio global

SKUGTIN
C8261-500MG04061833619117
C8261-1G04061833521984

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