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CBL511

Sigma-Aldrich

Anti-CD55 Antibody, clone BRIC 216

clone BRIC 216, Chemicon®, from mouse

Sinônimo(s):

DAF

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.

fonte biológica

mouse

Nível de qualidade

100

forma do anticorpo

affinity purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

BRIC 216, monoclonal

reatividade de espécies

human

fabricante/nome comercial

Chemicon®

técnica(s)

flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG1

nº de adesão NCBI

NM_000574.2

nº de adesão UniProt

P08174

Condições de expedição

wet ice

Informações sobre genes

human ... CD55(1604)

Especificidade

This antibody recognizes the CD55 antigen a 70 kDa glycoprotein also known as Decay Accelerating Factor (DAF). The antigen is present on erthrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. It is found specifically at the placental fetal-maternal interface.

Imunogênio

Human fibroblast cell line

Aplicação

Anti-CD55 Antibody, clone BRIC 216 is an antibody against CD55 for use in FC, IP, WB, IH, IH(P).
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Western blot: Non-reduced erythrocyte membrane prep; antigen is sialidase and trypsin resistant, pronase, chymotrypsin and AET sensitive
Flow Cytometry
Immunohistochemistry: Frozen and formalin-fixed paraffin-embedded sections. Protease antigen retreival is recommended.
Immunoprecipitation
Inhibition studies


Optimal working dilutions must be determined by the end user.

forma física

Format: Purified
Protein G Purified
The immunoglobulin was purified from cell culture supernatant by affinity chromatography using protein G and is presented in 1 M Tris-buffered saline, pH 7.5, containing no preservatives. The antibody has been sterile-filtered.

Armazenamento e estabilidade

Aliquot antibody into small volumes and store at -20°C for up to 12 months from the date of receipt.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Preferential expression of the complement regulatory protein decay accelerating factor at the fetomaternal interface during human pregnancy.
Holmes, C H, et al.
Journal of immunology (Baltimore, Md. : 1950), 144, 3099-3105 (1990)
Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor.
Coyne, K E, et al.
Journal of immunology (Baltimore, Md. : 1950), 149, 2906-2913 (1992)
Kyle A Carver et al.
Investigative ophthalmology & visual science, 57(2), 360-371 (2016-02-05)
Oxidative stress is a major factor involved in retinal pigment epithelium (RPE) apoptosis that underlies AMD. Drusen, extracellular lipid- and protein-containing deposits, are strongly associated with the development of AMD. Cell-derived microparticles (MPs) are small membrane-bound vesicles shed from cells.

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