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GW22692

Sigma-Aldrich

Anti-CD55 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinônimo(s):

Anti-CD55

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About This Item

Número MDL:
MFCD00675552
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

chicken

Nível de qualidade

200

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

reatividade de espécies

human

fabricante/nome comercial

Genway 15-288-22692

técnica(s)

western blot: suitable

nº de adesão NCBI

NP_000565.1

nº de adesão UniProt

P08174

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... CD55(1604)

Categorias relacionadas

Imunogênio

Immunogen Sequence: GI # 10835143, sequence 36-129
Recombinant decay accelerating factor for complement

Aplicação

Anti-CD55 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Ações bioquímicas/fisiológicas

Complement decay-accelerating factor (decay-accelerating factor, DAF) is a protein encoded by the CD55 gene in humans. It plays multiple functions including tissue protection from the cytotoxic complement injury and an anti-inflammatory function due to its anti-adherence properties. It is essential in many organ systems including pregnancy for protection of the semiallogeneic fetus or for preventing uncontrolled infiltration by white cells in their pro- and/or anti-inflammatory functions. Expression of CD55 appears to have multiple regulatory tissue-specific and/or menstrual cycle-specific mechanisms that are involved in complex signaling mechanisms. Its regulation may involve a direct or an indirect effect of at least the estrogen, progesterone, and corticosteroid regulatory pathways. It plays a a primary role in conferring resistance to lysis. CD55 is overexpressed in several types of cancer.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Yanxia Wu et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(12), G1056-G1064 (2014-04-26)
Engineering cancer cells to express heterologous antigen α-gal and induce the destruction of tumor cells depending on the complement cascade may be a promising strategy of tumor therapy. However, the feasibility and effect of using α-gal to induce colorectal adenocarcinoma
Bogdan Nowicki et al.
Advances in experimental medicine and biology, 735, 83-96 (2013-02-14)
In this chapter, we present a concise historic prospective and a summary of accumulated knowledge on steroid hormones, DAF expression, and therapeutic implication of steroid hormone treatment on multiple pathologies, including infection and the host-pathogen interactions. DAF/CD55 plays multiple physiologic
E D Vainer et al.
Tissue antigens, 82(1), 26-34 (2013-05-23)
CD55 (decay-accelerating factor, DAF) is overexpressed in several types of cancer, including colorectal cancer. Because of its inhibitory effect on the complement system, it has been suggested as a possible target for cancer immunotherapy. However, CD55 is also expressed in

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