1316004

Hidrocortisona

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): 11β,17α,21-Tri-hidroxipregna-4-eno-3,20-diona, 17-Hidroxicorticosterona, 4-Pregneno-11β,17α,21-triol-3,20-diona, Composto F de Kendall, Cortisol, Substância M de Reichstein
• Fórmula empírica (Notação de Hill): C₂₁H₃₀O₅
• Número CAS: 50-23-7
• Peso molecular: 362.46
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750063
• MDL number: MFCD00011654
• Beilstein/REAXYS Number: 1354819

Propriedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: hydrocortisone
• manufacturer/tradename: USP
• mp: 211-214 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
• InChI: 1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChI key: JYGXADMDTFJGBT-VWUMJDOOSA-N
• Gene Information: human ... NR3C1(2908)

Descrição

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrocortisone USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard stock, standard, and system suitability solution for assay, identification, and performance test by liquid chromatography in accordance with the given below monographs of United States Pharmacopeia (USP) :

• Hydrocortisone Sodium Succinate for Injection
• Hydrocortisone Tablets
• Hydrocortisone Gel
• Hydrocortisone Lotion

Biochem/physiol Actions

Glicocorticoide primário secretado pelo córtex adrenal.

Glicocorticoide primário secretado pelo córtex adrenal. Tem três vezes a potência anti-inflamatória da corticosterona, mas uma potência de retenção de Na²⁺ muito menor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informações de segurança

• pictograms: GHS08
• signalword: Danger
• hcodes: H360Df,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1A - STOT RE 2
• Classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• target_organs: Adrenal gland,Bone marrow