C8667

Cholesterol

Sigma Grade, ≥99%

• Synonim(y): 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol
• Wzór empiryczny (zapis Hilla): C₂₇H₄₆O
• Numer CAS: 57-88-5
• Masa cząsteczkowa: 386.65
• Beilstein: 1915888
• Numer WE: 200-353-2
• Numer MDL: MFCD00003646
• Kod UNSPSC: 12352111
• eCl@ss: 39023139
• Identyfikator substancji w PubChem: 24893094
• NACRES: NA.77

Właściwości

• pochodzenie biologiczne: sheep wool
• klasa czystości: Sigma Grade
• Próba: ≥99%
• Postać: powder
• tw: 360 °C (lit.)
• mp: 147-149 °C (lit.)
• rozpuszczalność: water: soluble 0.00003 g/L at 20 °C
• gęstość: 1.067 g/mL at 25 °C (lit.)
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• ciąg SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• Klucz InChI: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• informacje o genach: human ... POLA1(5422) , TOP2A(7153) ; rat ... Ar(24208) , Polb(29240)

Opis

Zastosowanie

Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.

Standard for chromatography

Działania biochem./fizjol.

Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Uwaga dotycząca przygotowania

Cholesterol monohydrate yields a clear, colorless to faint yellow solution in hot alcohol. It is also soluble in acetone, dioxane, ethyl acetate, benzene, petroleum ether, oils, fats, and in aqueous solutions of bile salts. Solutions should be protected from light.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)