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MAB1978

Anti-Integrin αV (ITGAV/CD51) Antibody

Name: Anti-Integrin αV (ITGAV/CD51) Antibody
Brand: MM
Price: 1950 PLN

CHEMICON^®, mouse monoclonal, LM142

Synonim(y):

CD51

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Gabaryty przesyłki	SKU	Dostępność	Cena netto
100 μL		Sprawdź dostępność w koszyku	1950,00 zł

Informacje o tej pozycji

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Clone:

LM142, monoclonal

Species reactivity:

human

Application:

IHC, IP

Citations:

1950,00 zł

Sprawdź dostępność w koszyku

Rekombinowane, niezawierające konserwantów przeciwciało jest dostępne dla Twojego celu. Wypróbuj ZMS1053

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Nazwa produktu

Anti-Integrin αV Antibody, clone LM142, ascites fluid, clone LM142, Chemicon^®

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

LM142, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon^®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable

isotype

IgG1

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Ta pozycja	CBL490	MAB2021Z	MAB1953
Sigma-Aldrich MAB1978 Anti-Integrin αV Antibody, clone LM142	Sigma-Aldrich CBL490 Anti-Integrin αV Antibody, clone 13C2	Sigma-Aldrich MAB2021Z Anti-Integrin αV Antibody, extracellular, clone AV1, azide free	Sigma-Aldrich MAB1953 Anti-Integrin αV Antibody, clone P3G8
Gene Information human ... ITGAV(3685)	Gene Information human ... ITGAV(3685)	Gene Information human ... ITGAV(3685)	Gene Information human ... ITGAV(3685)
clone LM142, monoclonal	clone 13C2, monoclonal	clone AV1, monoclonal	clone P3G8, monoclonal
species reactivity human	species reactivity human	species reactivity human	species reactivity human
biological source mouse	biological source mouse	biological source mouse	biological source mouse
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form culture supernatant	antibody form purified antibody
technique(s) immunohistochemistry: suitable, immunoprecipitation (IP): suitable	technique(s) flow cytometry: suitable, immunohistochemistry: suitable	technique(s) flow cytometry: suitable, western blot: suitable	technique(s) ELISA: suitable, flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable

Application

Detect Integrin αV using this Anti-Integrin αV Antibody, clone LM142 validated for use in IP, IH.

Immunohistochemistry (Acetone Fixed Only) 1:1000

Immunofluorescence and immunoprecipitation.

MAB1978 is non-blocking.

Final working dilutions must be determined by end user.

Research Category
Cell Structure

Research Sub Category
Integrins

Biochem/physiol Actions

Reactive with integrin alpha-V.

Preparation Note

Maintain at -20°C for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Numer produktu

Opis

Cennik

ZMS1053

Anti-Integrin αV Antibody, clone 272-17E6 ZooMAb^® Mouse Monoclonal, recombinant, expressed in HEK 293 cells

Klasa składowania

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certyfikaty analizy (CoA)

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A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins.

Tobias G Kapp et al.

Scientific reports, 7, 39805-39805 (2017-01-12)

Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in specific integrins, or their deregulated expression, are associated with a variety of diseases.

Many alphaIIbbeta3 autoepitopes in chronic immune thrombocytopenic purpura are localized to alphaIIb between amino acids L1 and Q459.

Robert McMillan et al.

British journal of haematology, 118(4), 1132-1136 (2002-08-30)

In chronic immune thrombocytopenic purpura (ITP), autoantibodies bind to platelet surface proteins, particularly alphaIIb, resulting in platelet destruction by the reticulo-endothelial system. In order to better localize the autoepitopes on alphaIIb, we studied the binding of antibodies to Chinese hamster

αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion.

Tatiana Gianni et al.

PLoS pathogens, 9(12), e1003806-e1003806 (2013-12-25)

Herpes simplex virus (HSV)--and herpesviruses in general--encode for a multipartite entry/fusion apparatus. In HSV it consists of the HSV-specific glycoprotein D (gD), and three additional glycoproteins, gH/gL and gB, conserved across the Herpesviridae family and responsible for the execution of

Integrin alpha v beta 5-dependent serine phosphorylation of paxillin in cultured human macrophages adherent to vitronectin.

M O De Nichilo et al.

The Journal of biological chemistry, 271(18), 11016-11022 (1996-05-03)

The macrophage colony-stimulating factor (M-CSF) is able to induce the expression of the alpha v beta 5 integrin receptor on the surface of cultured human macrophages (De Nichilo, M. O., and Burns, G. F. (1993) Proc. Natl. Acad. Sci. U.S.A.

CD47-dependent molecular mechanisms of blood outgrowth endothelial cell attachment on cholesterol-modified polyurethane.

Masako Ueda et al.

Biomaterials, 31(25), 6394-6399 (2010-06-12)

We previously showed that blood outgrowth endothelial cells (BOECs) had a high affinity for polyurethane (PU) covalently configured with cholesterol residues (PU-Chol). However, the molecular mechanisms responsible for this enhanced affinity were not determined. CD47, a multifunctional transmembrane glycoprotein involved

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Powiązane treści

Data Sheet - MAB1978

MOUSE ANTI-HUMAN INTEGRIN alpha-V

Numer pozycji handlu globalnego

SKU	NUMER GTIN
MAB1978	04053252700378

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