SML0972

ORM-10103

≥98% (HPLC)

• Synonim(y): 2-[(3,4-Dihydro-2-phenyl-2H-1-benzopyran-6-yl)oxy]-5-nitro-pyridine
• Wzór empiryczny (zapis Hilla): C₂₀H₁₆N₂O₄
• Numer CAS: 488847-28-5
• Masa cząsteczkowa: 348.35
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to light brown
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: room temp
• SMILES string: [N+](=O)([O-])c1cnc(cc1)Oc2cc3c(cc2)OC(CC3)c4ccccc4
• InChI: 1S/C20H16N2O4/c23-22(24)16-7-11-20(21-13-16)25-17-8-10-19-15(12-17)6-9-18(26-19)14-4-2-1-3-5-14/h1-5,7-8,10-13,18H,6,9H2
• InChI key: GZONLGPIHCCJOI-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

ORM-10103 is a potent, specific inhibitor of the Na(+)/Ca(2+) exchanger, NCX.

ORM-10103 is a potent, specific inhibitor of the Na(+)/Ca(2+) exchanger, NCX. The compound ORM-10103 inhibits both inward and outward NCX currents with IC₅₀ values of 780 nM, and 960 nM, respectively. ORM-10103 blocks induced arrhythmias in canine cardiac tissue.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H413
• pcodes: P264 - P270 - P273 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable