SML0851

GZ-793A

≥98% (HPLC)

• Synonim(y): (R)-3-[2,6-cis-Di(4-methoxyphenethyl)piperidin-1-yl]propane-1,2-diol hydrochloride, 3-[(2R,6S)-2,6-Bis[2-(4-methoxyphenyl)ethyl]-1-piperidinyl]-(2R)-1,2-propanediol hydrochloride
• Wzór empiryczny (zapis Hilla): C₂₆H₃₇NO₄ · HCl
• Numer CAS: 1356447-90-9
• Masa cząsteczkowa: 464.04
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Quality level: 100

Właściwości

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 3 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Cl.N1([C@H](CCC[C@H]1CCc3ccc(cc3)OC)CCc2ccc(cc2)OC)C[C@@H](O)CO
• InChI: 1S/C26H37NO4.ClH/c1-30-25-14-8-20(9-15-25)6-12-22-4-3-5-23(27(22)18-24(29)19-28)13-7-21-10-16-26(31-2)17-11-21;/h8-11,14-17,22-24,28-29H,3-7,12-13,18-19H2,1-2H3;1H/t22-,23+,24-;/m1./s1
• InChI key: FLFFCQKGCYZDOI-SJUVJREQSA-N

Opis

Biochem/physiol Actions

GZ-793A is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2), which transports the monoamine neurotransmitters from cellular cytosol into synaptic vesicles. GZ-793A is 50-fold selective for VMAT over the serotonin or dopamine transporters. VMAT2 has recently been considered a target for the treatment of methamphetamine abuse. In rat studies, GZ-793A decreased self-administration of methamphetamine with no development of tolerance.

GZ-793A is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2).

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Informacja o środkach bezpieczeństwa

• pictograms: GHS09
• signalword: Warning
• hcodes: H410
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable