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S0375

D-Saccharic acid 1,4-lactone monohydrate

≥98.0% (HPLC)

Synonim(y):

D-Glucaric acid-1,4-lactone, D-Saccharolactone

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Gabaryty przesyłkiSKUDostępnośćCena netto
250 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
411,00 zł
1 g
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1000,00 zł
5 g
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4310,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C6H8O7 · H2O
Numer CAS:
Masa cząsteczkowa:
210.14
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
85594

411,00 zł


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Quality Level

assay

≥98.0% (HPLC)

form

powder

impurities

≤10.0% water (Karl Fischer)

color

white

mp

91 - 93 °C ((196 - 199 °F ))

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O

InChI

1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1

InChI key

NPFKVZHSFSFLPU-QGBSHYGGSA-N

General description

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).

Application

D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Ta pozycja
85145079469L254
assay

≥98.0% (HPLC)

assay

≥99%

assay

≥97.0% (HPLC)

assay

-

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

water: soluble 25 mg/mL, clear, colorless

solubility

-

solubility

-

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

200

form

powder

form

powder

form

crystals

form

powder

storage temp.

2-8°C

storage temp.

-

storage temp.

−20°C

storage temp.

-

color

white

color

-

color

white

color

-


Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



Syed Ahmad et al.
Current chemical genomics, 5, 13-20 (2011-06-07)
CPT-11 is a widely-used anti-cancer drug that is converted in vivo to its active metabolite, SN-38. In the liver, enzymes detoxify SN-38 by coupling it to a glucuronidate moiety and this inactive compound (SN-38G) is excreted into the gastrointestinal tract.
beta-Klotho as a Negative Regulator of the Peptide Transporters PEPT1 and PEPT2
Abousaab A, et al.
Cellular Physiology and Biochemistry, 40(5), 874-882 (2016)
Gertrud E Morlock et al.
Antioxidants (Basel, Switzerland), 10(1) (2021-01-21)
The antioxidative activity of Camelia sinensis tea and especially powdered tea extracts on the market, among others used as added value in functional foods, can considerably vary due to not only natural variance, but also adulteration and falsification. Thus, an



Numer pozycji handlu globalnego

SKUNUMER GTIN
S0375-5G04061832393100
S0375-25G04061835367580
S0375-250MG04061835367573
S0375-1G04061836830236

Questions

1–3 of 3 Questions  
  1. Does this product can be store in solution? and for how much time?

    1 answer
    1. The stability of this product in solution has not been determined. The solubility of this material is tested at 50 mg/mL. Other sources report that this compound is also soluble at 100 mg/mL in DMSO. In addition, prepared solutions are stable for 1 month at -20°C and 6 months at -80°C. This information has not been validated.

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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