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G1001

D-Glutamic acid

≥99% (TLC), suitable for ligand binding assays

Synonim(y):

(R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(−)-1-Aminopropane-1,3-dicarboxylic acid

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Gabaryty przesyłkiSKUDostępnośćCena netto
1 g
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120,00 zł
5 g
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266,00 zł
25 g
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996,00 zł
100 g
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2940,00 zł

Informacje o tej pozycji

Wzór liniowy:
HO2CCH2CH2CH(NH2)CO2H
Numer CAS:
Masa cząsteczkowa:
147.13
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
230-000-8
MDL number:
Beilstein/REAXYS Number:
1723800

120,00 zł


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Nazwa produktu

D-Glutamic acid, ≥99% (TLC)

Quality Level

assay

≥99% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

mp

200-202 °C (subl.) (lit.)

SMILES string

N[C@H](CCC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1

InChI key

WHUUTDBJXJRKMK-GSVOUGTGSA-N

Gene Information

human ... CCR2(1231)

General description

D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor.[1] Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.[2]

Application

D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.[2]

Biochem/physiol Actions

Unnatural isomer of glutamic acid.
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Ta pozycja
1.00291G0355000W328502
Glutamic acid European Pharmacopoeia (EP) Reference Standard

G0355000

Glutamic acid

form

powder

form

solid

form

-

form

powder or crystals

assay

≥99% (TLC)

assay

≥99% substance (anhydrous) basis (alkalimetric)

assay

-

assay

98.5-101.5% dry basis (perchloric acid titration)

technique(s)

ligand binding assay: suitable

technique(s)

-

technique(s)

-

technique(s)

-

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

300, 400

mp

200-202 °C (subl.) (lit.)

mp

160 °C

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

color

white to off-white

color

-

color

-

color

-


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Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



Matthew Volgraf et al.
Nature chemical biology, 2(1), 47-52 (2006-01-13)
The precise regulation of protein activity is fundamental to life. The allosteric control of an active site by a remote regulatory binding site is a mechanism of regulation found across protein classes, from enzymes to motors to signaling proteins. We
Katie L Whalen et al.
Molecular informatics, 30(5), 459-471 (2011-07-09)
Existing techniques which attempt to predict the affinity of protein-ligand interactions have demonstrated a direct relationship between computational cost and prediction accuracy. We present here the first application of a hybrid ensemble docking and steered molecular dynamics scheme (with a
P Doublet et al.
Journal of bacteriology, 174(18), 5772-5779 (1992-09-01)
The murI gene of Escherichia coli, whose inactivation results in the inability to form colonies in the absence of D-glutamic acid, was identified in the 90-min region of the chromosome. The complementation of an auxotrophic E. coli B/r strain by



Numer pozycji handlu globalnego

SKUNUMER GTIN
G1001-5G04061833624623
G1001-100G04061833624593
G1001-1G04061833624609
G1001-25G04061833624616

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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