C0868

Chromeceptin

≥98% (HPLC), solid

• Synonim(y): 2-Amino-3-cyano-7-dimethylamino-4-(3-trifluoromethylphenyl)-4H-chromene, 94G6
• Wzór empiryczny (zapis Hilla): C₁₉H₁₆F₃N₃O
• Numer CAS: 331859-86-0
• Masa cząsteczkowa: 359.35
• NACRES: NA.77
• PubChem Substance ID: 24724431
• UNSPSC Code: 51111800
• MDL number: MFCD00815850
• Assay: ≥98% (HPLC)
• Form: solid
• Quality level: 100

Właściwości

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• color: yellow to brown
• solubility: H₂O: <2 mg/mL, DMSO: >20 mg/mL
• storage temp.: −20°C
• SMILES string: CN(C)c1ccc2C(c3cccc(c3)C(F)(F)F)C(C#N)=C(N)Oc2c1
• InChI: 1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3
• InChI key: GVINXTXGDDSXFQ-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Chromeceptin binds to multifunctional protein 2 (MFP-2); inhibits Insulin-like growth factor 2 (IGF2) signaling.

Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals.

Features and Benefits

This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable