This product is not excipient grade. It is a research grade material intended for R&D use only.
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D6518
Diethylenetriaminepentaacetic acid
≥99% (titration)
Synonim(y):
(Carboxymethylimino)bis(ethylenenitrilo)tetraacetic acid, N,N-Bis(2-[bis(carboxymethyl)amino]ethyl)glycine, DETAPAC, DTPA, Penta(carboxymethyl)diethylenetriamine, Pentetic acid
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| Do Państwa/SKU | Dostępność | Cena netto |
|---|---|---|
5 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 535,00 zł |
10 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 907,00 zł |
50 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 2890,00 zł |
100 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 4380,00 zł |
Informacje o tej pozycji
Wzór liniowy:
[(HOOCCH2)2NCH2CH2]2NCH2COOH
Numer CAS:
Masa cząsteczkowa:
393.35
UNSPSC Code:
12352106
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-652-8
Beilstein/REAXYS Number:
1810219
MDL number:
535,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócbiological source
synthetic (organic)
Quality Segment
assay
≥99% (titration)
form
powder
mp
219-220 °C (lit.)
solubility
1 M HCl: 50 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O
InChI
1S/C14H23N3O10/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27)
InChI key
QPCDCPDFJACHGM-UHFFFAOYSA-N
General description
Diethylenetriaminepentaacetic acid is a diethylenetriaminepentaacetic anhydride, which is a bifunctional chelating agent. It is used for the treatment of poisoning.
Application
Diethylenetriaminepentaacetic acid has been used:
- for cofilin activity assay
- to determine the specificity of superoxide in the transverse aortic constriction (TAC) hearts
- for Europium bead-based detection assays
- to detect reduced (S- active) or irreversibly oxidized (SO3H inactive) tyrosine-protein phosphatase non-receptor type 6 (SHP-1) in thymocytes
Preparation Note
Purified
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Ta pozycja | |||
|---|---|---|---|
| assay ≥99% (titration) | assay ≥98% (titration) | assay - | assay - |
| biological source synthetic (organic) | biological source synthetic (organic) | biological source - | biological source - |
| Quality Level 200 | Quality Level 300 | Quality Level 300 | Quality Level 100 |
| form powder | form powder | form solid | form solid |
| storage temp. room temp | storage temp. room temp | storage temp. 2-30°C | storage temp. 15-25°C |
| solubility 1 M HCl: 50 mg/mL, clear, colorless | solubility 1 M HCl: 50 mg/mL, clear, colorless | solubility - | solubility 4.8 g/L |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
target_organs
Respiratory Tract
Klasa składowania
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
392.0 °F - closed cup
flash_point_c
200 °C - closed cup
Wykazy regulacyjne
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67-43-6
CAS No.
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Is D6518 Pentetic acid excipient grade?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What are the pKa values for Product D6518, Diethylenetriaminepentaacetic acid?
1 answer-
The pKa values for the carboxyl groups as reported in the reference book "Data for Biochemical Research, 3rd ed., page 402, Oxford University Press, New York (1986)." are 1.8, 2.6, 4.4, 8.8, and 10.4.
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How can I get Product D6518, Diethylenetriaminepentaacetic acid, to dissolve?
1 answer-
As is the case with other chelating agents such as EDTA and EGTA, the solubility of DTPA is a function of pH. Therefore, this compound can be solubilized with either the addition of acid such as a hydrochloric acid solution or (more likely) base such as a sodium hydroxide solution .
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What cations can be chelated with Product D6518, Diethylenetriaminepentaacetic acid (DTPA)?
1 answer-
DTPA forms stable complexes with most divalent and trivalent cations. Some examples are Fe3+, Cu2+, Ni2+, Pb2+, Zn2+, Fe2+, Mn2+, Ca2+, Mg2+, and Ba2+.
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