91230

Trichloroacetic acid

ACS reagent grade, ≥99.5% (T), flakes, for the determination of Fe in blood according to Heilmeyer

• Synonim(y): TCA
• Wzór liniowy: Cl₃CCOOH
• Numer CAS: 76-03-9
• Masa cząsteczkowa: 163.39
• NACRES: NA.21
• PubChem Substance ID: 57653429
• UNSPSC Code: 12352100
• EC Number: 200-927-2
• MDL number: MFCD00004177
• Beilstein/REAXYS Number: 970119
• Assay: ≥99.5% (T), ≥99.5%
• Form: flakes
• Grade: ACS reagent

Właściwości

• Nazwa produktu: Trichloroacetic acid, ACS reagent, for the determination of Fe in blood according to Heilmeyer, ≥99.5%
• grade: ACS reagent
• Quality Segment: 200
• vapor density: <1 (vs air)
• vapor pressure: 1 mmHg ( 51 °C)
• assay: ≥99.5% (T), ≥99.5%
• form: flakes
• quality: for the determination of Fe in blood according to Heilmeyer
• ign. residue: ≤0.03% (as SO₄)
• refractive index: n20/D 1.62 (lit.)
• bp: 196 °C (lit.)
• mp: 54-58 °C (lit.)
• solubility: water: soluble 81.7 g/L at 20 °C
• density: 1.62 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤10 mg/kg, nitrate (NO₃^-): ≤20 mg/kg, phosphate (PO₄^3-): ≤5 mg/kg, sulfate (SO₄^2-): ≤200 mg/kg
• cation traces: Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
• functional group: carboxylic acid, chloro
• SMILES string: OC(=O)C(Cl)(Cl)Cl
• InChI: 1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: YNJBWRMUSHSURL-UHFFFAOYSA-N

Opis

General description

Trichloroacetic acid (TCA) is a chlorinated acetic acid. It is one of the major metabolites of trichloroethylene (TCE).[1]

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Trichloroacetic acid may be used in the following studies:

• Estimation of phosphorus in various biological samples (serum, urine and stool ash solutions).[2]
• Elimination of acid-soluble and lipid phosphorous during the determination of deoxyribonucleic acid, ribonucleic acid and phosphoproteins in animal tissues.[3]
• Preparation of 2-methyl-4-nitroanilinium trichloroacetate trichloroacetic acid (2M4NATCA) crystals.[4]

10% Trichloroacetic acid may be employed for the preparation of radioactive proteins.[5]

Other Notes

Protein denaturant.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS05,GHS09
• signalword: Danger
• hcodes: H314,H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
• wgk: WGK 2
• flash_point_f: >235.4 °F - closed cup
• flash_point_c: > 113 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
• Klasa składowania: 8A - Combustible corrosive hazardous materials