03440

N-Ethyldiisopropylamine

≥98.0%, liquid

• Synonim(y): N,N-Diisopropylethylamine, Hünigs base
• Wzór liniowy: CH₃CH₂N[CH(CH₃)₂]₂
• Numer CAS: 7087-68-5
• Masa cząsteczkowa: 129.24
• NACRES: NA.21
• PubChem Substance ID: 329747703
• UNSPSC Code: 12352100
• EC Number: 230-392-0
• MDL number: MFCD00008868
• Beilstein/REAXYS Number: 605301
• Assay: ≥98.0%
• Form: liquid

Właściwości

• Nazwa produktu: N-Ethyldiisopropylamine, ≥98.0%
• Quality Level: 200
• assay: ≥98.0%
• form: liquid
• impurities: ≤0.5% water
• refractive index: n20/D 1.414
• bp: 126-128 °C (lit.)
• density: 0.755 g/mL at 20 °C, 0.757 g/mL at 25 °C (lit.)
• functional group: amine
• SMILES string: CCN(C(C)C)C(C)C
• InChI: 1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3
• InChI key: JGFZNNIVVJXRND-UHFFFAOYSA-N

Opis

General description

N,N-Diisopropylethylamine (DIPEA), also known as Hunig′s base, is a sterically hindered amine. It is a non-nucleophilic base commonly employed in substitution reactions, alkylations, and amide couplings, etc. DIPEA is also used as a base in the Pd catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions.

Application

• Catalytic activity in dioxygen reduction: A study utilized Mn complexes with pendent proton donor relays and added base, including N-Ethyldiisopropylamine, to control product selectivity during dioxygen reduction, providing insights into catalytic mechanisms and potential industrial applications (Cook et al., 2024).


• Three-dimensional imaging in medical applications: N-Ethyldiisopropylamine was mentioned in the context of its role in improving the resolution of three-dimensional imaging techniques based on computed tomography angiography (CTA), crucial for preoperative perforator selection in reconstructive surgery (Su et al., 2024).


• Synthesis of Spirocyclopropane-Containing Compounds: Research demonstrated the application of N-Ethyldiisopropylamine in the synthesis of spirocyclopropane-containing 4H-pyrazolo[1,5-a]indoles through alkylative dearomatization and intramolecular N-imination, highlighting its utility in complex organic synthesis (Huang et al., 2023).

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Informacja o środkach bezpieczeństwa

• pictograms: GHS02,GHS06,GHS05,GHS09
• signalword: Danger
• hcodes: H225,H302,H318,H331,H335,H411
• pcodes: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 3 - Flammable liquids
• wgk: WGK 2
• flash_point_f: 49.1 °F
• flash_point_c: 9.5 °C
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter