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OP44

Anti-APC (Ab-1) Mouse mAb (FE9)

liquid, clone FE9, Calbiochem®

Synonim(y):

Anti-Adenomatous Polyposis Coli

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Gabaryty przesyłkiSKUDostępnośćCena netto
100 μg
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2180,00 zł

Informacje o tej pozycji

NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
FE9, monoclonal
Species reactivity:
rat, human, mouse
Application:
Citations:
23

2180,00 zł


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biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

FE9, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

rat, human, mouse

manufacturer/tradename

Calbiochem®

storage condition

do not freeze

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Ta pozycja
WH0000324M1MABC202HPA013349
species reactivity

rat, human, mouse

species reactivity

human

species reactivity

human

species reactivity

human

Gene Information

human ... APC(324)

Gene Information

human ... APC(324)

Gene Information

human ... APC(324)

Gene Information

human ... APC(324)

clone

FE9, monoclonal

clone

3E2, monoclonal

clone

FE9, monoclonal

clone

polyclonal

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

biological source

mouse

biological source

mouse

biological source

mouse

biological source

rabbit

shipped in

wet ice

shipped in

dry ice

shipped in

wet ice

shipped in

wet ice

General description

Recognizes full length APC (p300) in HCT116 cells and truncated APC (p147) in SW480 cells.
  • Antibody Target Gene Symbol: APC
  • Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC
  • Entrez Gene Name: adenomatous polyposis coli
  • Hu Entrez ID: 324 (Related Antibodies: OP80, ST1150, OP62, OP47L)
  • Mu Entrez ID: 11789
  • Rat Entrez ID: 24205
Anti-APC (Ab-1), mouse monoclonal, clone FE9, recognizes full length APC (p300) in HCT116 cells and truncated APC (p147) in SW480 cells. It is validated for Western botting.
Protein G purified mouse monoclonal antibody generated by immunizing mice with the specified immunogen and fusing splenocytes with SP40 cells. Recognizes the ~300 kDa APC protein as well as a variety of truncated forms.

Immunogen

a synthetic peptide corresponding to the N-terminal 35 amino acids of APC

Application

Immunoblotting (1 µg/ml, see comments)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 50 mM sodium phosphate buffer, pH 7.5, 0.2% gelatin.

Analysis Note

Positive Control
HCT116 cells for p300, SW480 cells for truncated APC (p147)

Other Notes

Koetsier, P. A., et al. 1993. BioTechniques15, 258.
Smith, K. J., et al. 1993. Proc. Natl. Acad. Sci., USA90, 2846.
Su, L.-K., et al. 1993. Can. Res.53, 2728.
Boynton, R. F., et al. 1992. Proc. Natl. Acad. Sci. USA89, 3385.
D′Amico, D., et al. 1992. Cancer Res.52, 1996.
Fearon, E. R., and Jones, P. A., 1992. FASEB J.6, 2783.
Miyoshi, Y., et al. 1992. Proc. Natl. Acad. Sci. USA89, 4452.
Powell, S. M., et al. 1992. Nature359, 235.
Groden, J., et al. 1991. Cell66, 589.
Kinzler, K. W., et al. 1991. Science253, 661.
Nishisho, I., et al. 1991. Science253, 665.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)
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Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certyfikaty analizy (CoA)

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Jason L Larabee et al.
The Journal of biological chemistry, 286(22), 19364-19372 (2011-04-14)
The production of cAMP from Bacillus anthracis edema toxin (ET) activates gene expression in macrophages through a complex array of signaling pathways, most of which remain poorly defined. In this study, the tumor suppressor protein adenomatous polyposis coli (APC) was
Tamar Evron et al.
Oncogenesis, 10(9), 63-63 (2021-09-24)
The Wnt signaling pathways play fundamental roles during both development and adult homeostasis. Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including cancer, and is especially implicated in the development and progression of colorectal
Dipon Das et al.
DNA repair, 24, 15-25 (2014-12-03)
Colorectal cancer (CRC) patients with APC mutations do not benefit from 5-FU therapy. It was reported that APC physically interacts with POLβ and FEN1, thus blocking LP-BER via APC's DNA repair inhibitory (DRI) domain in vitro. The aim of this
Mireia Menéndez et al.
Gastroenterology, 134(1), 56-64 (2008-01-02)
We identified the APC N1026S variant of unknown malignant potential in the adenomatous polyposis coli (APC) gene in a Spanish attenuated familial adenomatous polyposis (AFAP) family. The variant was located in the first of the 4 highly conserved 15-amino acid
Hideaki Toki et al.
Cancer science, 104(7), 937-944 (2013-04-05)
Mutant mouse models are indispensable tools for clarifying the functions of genes and elucidating the underlying pathogenic mechanisms of human diseases. We carried out large-scale mutagenesis using the chemical mutagen N-ethyl-N-nitrosourea. One specific aim of our mutagenesis project was to

Numer pozycji handlu globalnego

SKUNUMER GTIN
OP44-100UG04055977227130

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