MAB5504

Anti-Vesicular Glutamate Transporter 2 Antibody

clone 8G9.2, Chemicon^®, from mouse

• Synonim(y): VGLUT2
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: 8G9.2, monoclonal
• Application: IHC, WB
• Citations: 123

Właściwości

• biological source: mouse
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 8G9.2, monoclonal
• species reactivity: mouse, rat
• species reactivity (predicted by homology): human
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable, western blot: suitable
• isotype: IgG1
• NCBI accession no.: NM_020346.1
• UniProt accession no.: Q9JI12
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SLC17A6(57084)

Opis

General description

Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.

56 kDa

Application

Detect Vesicular Glutamate Transporter 2 using this Anti-Vesicular Glutamate Transporter 2 Antibody validated for use in WB, IH.

Immunohistochemistry: A 1:50-1:300 dilution of a previous lot worked using ABC with NiDAB on floating mouse brain sections.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with VGLUT2 (Vesicular Glutamate Transporter 2).

Physical form

Format: Purified

Mouse monoclonal in PBS containing 0.1% sodium azide.

Analysis Note

Evaluated by Western Blot on Mouse brain lysates.

Western Blotting Analysis: 1:500 dilution of this antibody detected VGLUT2 on 10 µg of Mouse brain lysates.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

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• wgk: WGK 2