MAB1612

Anti-Cytokeratin Epithelial Antibody, clone AE1

clone AE1, Chemicon^®, from mouse

• Synonim(y): Anti-K2C8, Anti-CARD2, Anti-CK8, Anti-CYK8, Anti-K8, Anti-KO
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: AE1, monoclonal
• Application: IHC
• Citations: 11

Właściwości

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: AE1, monoclonal
• species reactivity: mouse, chicken, human, rabbit, bovine, rat
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable (paraffin)
• isotype: IgG
• NCBI accession no.: NM_002273.2
• UniProt accession no.: P05787
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... KRT1(3848) ; rat ... Krt19(360626)

Opis

Immunogen

Human epidermal keratin

Application

Immunohistochemistry on unfixed frozen sections and formalin-fixed paraffin embedded tissues. Antigen retrieval is recommended. HEIR or protease treatment can be used.

Western Blotting: AE1 recognizes LMW cytokeratins from the acidic subfamily including: Clone AE1 recognises the 56.5, 50, 50′, 48 and 40kD human cytokeratins of the acidic subfamily.

Optimal working dilutions must be determined by end user.

Research Category
Cell Structure

Research Sub Category
Cytokeratins

This Anti-Cytokeratin Epithelial Antibody, clone AE1 is validated for use in IH(P) for the detection of Cytokeratin Epithelial.

Biochem/physiol Actions

Recognizes most of the acidic (Type I) keratins. It is broadly reactive and stains positively almost all epithelia and their neoplasms. MAB1612 produces heterogeneous staining within a given epithelium; the detailed staining pattern varies depending on the differentiated and/or growth state of individual cells.

Physical form

Format: Purified

Liquid in 0.05M Borate Buffered Saline, 0.15M NaCl, 0.09% Sodium Azide, pH8.2.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: 04-588

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08
• signalword: Danger
• hcodes: H360FD
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Klasa składowania: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable