GF302

BMP-4 Protein, Human Recombinant Animal Free

Bone morphogenetic protein 4 (BMP4) is a TGFβ superfamily lig& that is widely expressed from early embryogenesis through adulthood. The Recombinant animal free human BMP-4 protein is manufactured using all non-animal reagents.

• Synonim(y): BMP4, Bone morphogentic protein-4, DVR-4
• Kod UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.77

Właściwości

• rekombinowane: expressed in E. coli
• Poziom jakości: 100
• Próba: >98% (SDS-PAGE and HPLC)
• zanieczyszczenia: <0.1 μg/mg protein endotoxin (<1EU/μg)
• numer dostępu NCBI: NM_001202.3; NM_130850.2; NM_130851.2
• numer dostępu UniProt: P12644
• Warunki transportu: dry ice

Opis

Opis ogólny

Bone morphogentic protein 4 (BMP4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
Animal free human recombinant BMP4 is a fully active homodimeric protein consisting of two 107 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.

Product Source: E. coli

Specyficzność

Cross Reactivty
Mouse

Zastosowanie

Research Category
Stem Cell Research

Research Sub Category
Growth Factors & Receptors

Jakość

Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.

Postać fizyczna

Product is filtered through a 0.2 micron filter before lyophilization.

Recombinant animal free human BMP-4 is manufactured using all non-animal reagents

Przechowywanie i stabilność

Store at -20°C for up to 6 months from date of receipt.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable