AP502
Goat Anti-Human Ig κ chain Antibody, Species Adsorbed
1 mg/mL, Chemicon®
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About This Item
Polecane produkty
pochodzenie biologiczne
goat
Poziom jakości
forma przeciwciała
affinity purified immunoglobulin
rodzaj przeciwciała
secondary antibodies
klon
polyclonal
reaktywność gatunkowa
human
producent / nazwa handlowa
Chemicon®
stężenie
1 mg/mL
metody
ELISA: suitable
immunofluorescence: suitable
Warunki transportu
wet ice
docelowa modyfikacja potranslacyjna
unmodified
Opis ogólny
Antibody molecules typically comprise two immunoglobulin light chains covalently bound to a pair of heavy chains. Immunoglobulin light chains occur in two types, designated by the Greek letters kappa and lambda. Kappa and lambda light chains are approximately 250 amino acids in length with an average mass of about 25 kDa. The ratio of kappa to lambda found in the immunoglobulin population varies by species.
Specyficzność
Reacts with human kappa light chains. Absorbed for human myeloma proteins with λ light chains and mouse immunoglobulins.
The antibody reacts with human kappa light chains as demonstrated by ELISA and flow cytometry.
Immunogen
Prepared from Ig kappa chain. Pooled antisera from goats hyperimmunized with human myeloma proteins with κ light chains.
Zastosowanie
Goat anti-Human Ig κ chain Antibody, Species Adsorbed detects level of Human Ig κ chain & has been published & validated for use in ELISA & IF.
Immunofluorescence: ≤ 1 μg/106 cells.
ELISA
Optimal working dilutions must be determined by the end user.
ELISA
Optimal working dilutions must be determined by the end user.
Research Category
Secondary & Control Antibodies
Secondary & Control Antibodies
Research Sub Category
Secondary Antibodies Adsorbed for Dual Labeling
Fragment Specific Secondary Antibodies
Secondary Antibodies Adsorbed for Dual Labeling
Fragment Specific Secondary Antibodies
Postać fizyczna
Affinity Chromatography
Format: Purified
Purified by affinity chromatography on pooled human Igs with κ light chains covalently linked to agarose. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.
Przechowywanie i stabilność
Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.
Informacje prawne
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
The Journal of biological chemistry, 292(6), 2328-2344 (2016-12-30)
Intervention into amyloid deposition with anti-amyloid agents like the polyphenol epigallocatechin-3-gallate (EGCG) is emerging as an experimental secondary treatment strategy in systemic light chain amyloidosis (AL). In both AL and multiple myeloma (MM), soluble immunoglobulin light chains (LC) are produced
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