This product is soluble in ethanol at a concentration of 5 mg/mL. After reconstitution, aliquot and freeze at -20°C. Stock solutions remain stable for up to 1 month at -20°C.
181198
Kwas arachidonowy
≥99% (TLC and GC), oil, membrane phospholipid component, Calbiochem®
Synonim(y):
cis,cis,cis,cis-5,8,11,14-kwas eikozatetraenowy, 20:4
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| Do Państwa/SKU | Dostępność | Cena netto |
|---|---|---|
100 mg | Przewidywany termin wysyłki25 maja 2026zKuehne + Nagel Sp. z o.o. | 672,00 zł |
1 g | Przewidywany termin wysyłki25 maja 2026zKuehne + Nagel Sp. z o.o. | 1640,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C20H32O2
Numer CAS:
Masa cząsteczkowa:
304.47
UNSPSC Code:
12352211
NACRES:
NA.77
MDL number:
Assay:
≥99% (TLC and GC)
Form:
oil
Storage condition:
OK to freeze, protect from light
Pomoc techniczna
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Pozwól nam pomócNazwa produktu
Kwas arachidonowy, Precursor for prostaglandins, prostacyclin, and thromboxane.
description
Merck USA index - 14, 765
Quality Segment
assay
≥99% (TLC and GC)
form
oil
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
colorless
solubility
ethanol: 5 mg/mL
shipped in
dry ice
storage temp.
−70°C
SMILES string
OC(=O)CCC\C=C\C\C=C\C\C=C\C\C=C\CCCCC
InChI
1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6+,10-9+,13-12+,16-15+
InChI key
YZXBAPSDXZZRGB-CGRWFSSPSA-N
General description
A cis-polyunsaturated fatty acid found in the plasma membrane. Major component of membrane phospholipids. Following its release by cellular phospholipases, it is enzymatically converted to a variety of inflammatory and vasoactive metabolites, such as prostaglandins (via the cyclooxygenase pathway), leukotrienes (via the lipoxygenase pathway), and epoxides (via the cytochrome P450 pathway). Binds to G-protein α-subunits in a covalent, posttranslational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets.
Precursor for prostaglandins, prostacyclin, and thromboxane. Binds to G-protein α-subunits in a covalent, post-translational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets. Modulates nitric oxide production by prostaglandin synthesis via the cyclooxygenase pathway.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Ras-GAP
Ras-GAP
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Other Notes
Hallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman P., et al. 1986. Annu. Rev. Biochem.55, 69.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman P., et al. 1986. Annu. Rev. Biochem.55, 69.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
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Ta pozycja | |||
|---|---|---|---|
| assay ≥99% (TLC and GC) | assay ≥98.5% (GC) | assay >99% (TLC) | assay ≥98.5% (GC) |
| form oil | form waxy solid | form ethanol solution | form liquid |
| Quality Level 100 | Quality Level 200 | Quality Level - | Quality Level 300 |
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename Avanti Research™ - A Croda Brand 861810E | manufacturer/tradename - |
| storage temp. −70°C | storage temp. −20°C | storage temp. −70°C | storage temp. −20°C |
| solubility ethanol: 5 mg/mL | solubility methanol: 50 mg/mL, clear, colorless to faintly yellow | solubility - | solubility - |
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Klasa składowania
10 - Combustible liquids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
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What is the preferred method for diluting and aliquoting the compound?
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What is the volume in uL of the 100mg AA vial? Why is it not stated on the vial?
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Please note that the density of this product is about 0.92 g/mL. Hence, 100 mg material has a volume of 108 microliters.
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