1.07427

Propyl 4-hydroxybenzoate

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, NF

• Synonim(y): Propyl 4-hydroxybenzoate, Propylparaben
• Wzór empiryczny (zapis Hilla): C₁₀H₁₂O₃
• Numer CAS: 94-13-3
• Masa cząsteczkowa: 180.20
• UNSPSC Code: 12352108
• EC Index Number: 202-307-7
• MDL number: MFCD00002354

Właściwości

• Quality Segment: 500
• agency: ChP, JP, NF, BP, Ph. Eur.
• vapor pressure: 0.67 hPa ( 122 °C)
• product line: EMPROVE^® EXPERT
• form: solid
• autoignition temp.: >600 °C
• potency: >5000 mg/kg LD₅₀, oral (Rat)
• technique(s): API processing | cocrystal formation: suitable
• pH: 6-7 (20 °C in H₂O, saturated solution)
• mp: 96-98 °C
• transition temp: flash point 180 °C
• solubility: 0.4 g/L
• density: 1.063 g/cm³ at 102 °C
• application(s): liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• SMILES string: O(CCC)C(=O)c1ccc(cc1)O
• InChI: 1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3
• InChI key: QELSKZZBTMNZEB-UHFFFAOYSA-N

Opis

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• hcodes: H412
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 356.0 °F
• flash_point_c: 180 °C