07-632
Przeciwciało anty-NR2A
Upstate®, from rabbit
Synonim(y):
Receptor N-metylo-D-asparaginianu podtyp 2A, receptor N-metylo-D-asparaginianu channe, podjednostka epsilon-1, receptor N-metylo-D-asparaginianu podjednostka 2A, receptor NMDA podtyp 2A, receptor glutaminianu, jonotropowy, N-metylo-D-asparaginian 2A
Wybierz wielkość
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 200 μg | Przewidywany termin wysyłki27 kwietnia 2026zKuehne + Nagel Sp. z o.o. | 2450,00 zł |
Informacje o tej pozycji
2450,00 zł
Przewidywany termin wysyłki27 kwietnia 2026Szczegóły
Quality Level
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... GRIN2A(2903)
General description
Immunogen
Application
4 µg poprzedniej partii poddano immunoprecypitacji NR2A z błon hipokampa mózgu szczura i preparatów mikrosomalnych mózgu szczura.
Neuroscience
Neuroprzekaźniki i receptory
Biochem/physiol Actions
Physical form
Preparation Note
Analysis Note
Tkanka mózgowa.
Western Blot Analysis:
0.5-2 µg/mL of this antibody detected NR2A in rat brain microsomal preparations (Catalog # 12-144).
Other Notes
Legal Information
Disclaimer
1 of 1
Ta pozycja | |||
|---|---|---|---|
| antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form affinity isolated antibody |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| species reactivity rat, mouse | species reactivity mouse, rat (based on 100% sequence homology) | species reactivity rat | species reactivity mouse, rat, human |
| biological source rabbit | biological source rabbit | biological source mouse | biological source rabbit |
| clone polyclonal | clone polyclonal | clone monoclonal | clone polyclonal |
| shipped in wet ice | shipped in dry ice | shipped in wet ice | shipped in dry ice |
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Klasa składowania
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Powiązane treści
Glutamate is an excitatory neurotransmitter found in the synaptic vesicles of glutamatergic synapses. The post-synaptic neurons in these synapses contain ionotropic and metabotropic glutamate receptors. Glutamate binds to AMPA (α-amino-3-hydroxy-5- methylisoxazole-4-propionic acid) subtype glutamate receptors, leading to sodium influx into the post-synaptic cell and resulting in neuronal excitability and synaptic transmission. The NMDA (N-methyl-d-aspartate) subtype glutamate receptors, on the other hand, regulate synaptic plasticity, and can influence learning and memory. The metabotropic g-protein coupled mGluRs modulate downstream calcium signaling pathways and indirectly influence the synapse’s excitability. The synaptic architecture includes intracellular scaffolding proteins (PSD-95, GRIP), intercellular cell adhesion molecules (NCAMs, N-Cadherins), and a variety of signaling proteins (CaMKII/PKA, PP1/PP2B). Processes critical for synaptic transmission and plasticity are influenced by these molecules and their interactions. When the function of these molecules is disrupted, it leads to synaptic dysfunction and degeneration, and can contribute to dementia as seen in Alzheimer’s disease.