1643306

Cytrynian tamoksyfenu

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): Tamoxifen citrate salt, (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
• Wzór empiryczny (zapis Hilla): C₂₆H₂₉NO · C₆H₈O₇
• Numer CAS: 54965-24-1
• Masa cząsteczkowa: 563.64
• NACRES: NA.24
• PubChem Substance ID: 329751221
• UNSPSC Code: 41116107
• MDL number: MFCD00058321

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: tamoxifen
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(=O)CC(O)(CC(O)=O)C(O)=O.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCN(C)C)cc3
• InChI: 1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;
• InChI key: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
• Gene Information: human ... ESR1(2099)

Opis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Wzorzec referencyjny cytrynianu tamoksyfenu USP, przeznaczony do stosowania w określonych testach jakości i testach określonych w kompendiach USP. Również do użytku z monografiami USP, takimi jak:

• Tamoxifen Citrate Tablets

Biochem/physiol Actions

Estrogen antagonist in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor.

Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H350,H360D,H410
• pcodes: P201 - P273 - P301 + P312 + P330 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable