1477604

Octan oktreotydu

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): Octreotide acetate salt
• Wzór empiryczny (zapis Hilla): C₄₉H₆₆N₁₀O₁₀S₂ · xC₂H₄O₂
• Numer CAS: 79517-01-4
• Masa cząsteczkowa: 1019.24 (free base basis)
• MDL number: MFCD08277638
• UNSPSC Code: 41116107
• NACRES: NA.24

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: octreotide
• form: powder
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• SMILES string: S1SCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C1)C(=O)N[C@@H]([C@H](O)C)CO)C(O)C)CCCCN)Cc4c5c([nH]c4)cccc5)Cc3ccccc3)NC(=O)C(N)Cc2ccccc2.OC(=O)C.OC(=O)C
• InChI: 1S/C49H66N10O10S2.2C2H4O2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41;2*1-2(3)4/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64);2*1H3,(H,3,4)/t28-,29?,34?,36?,37?,38?,39-,40?,41?,42?;;/m1../s1
• InChI key: QWFYIFWTVZFPRY-AARKYNAGSA-N

Opis

General description

Octreotide acetate is a synthetic cyclic octapeptide that mimics natural somatostatin, inhibiting the release of growth hormone, insulin, and glucagon. It is used therapeutically in acromegaly and neuroendocrine tumors. The USP reference standard enables identity, potency, and impurity testing in octreotide drug products.

The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Ten wzorzec referencyjny USP jest przeznaczony do stosowania w określonych testach jakości i oznaczeniach.
Używany również do przygotowania roztworów wzorcowych i odpowiednich dla systemu w oznaczeniu octanu oktreotydu, jak opisano w monografii Farmakopei Stanów Zjednoczonych (USP).

Analysis Note

Produkty te są przeznaczone wyłącznie do testów i oznaczeń. Nie są one przeznaczone do podawania ludziom lub zwierzętom i nie mogą być stosowane do diagnozowania, leczenia lub wyleczenia jakichkolwiek chorób.

Other Notes

Ten produkt jest częścią programu USP Biologics.

Sales restrictions may apply.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable