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T4382

apo-Transferrin human

powder, ≥98% (agarose gel electrophoresis)

Synonim(y):

Human transferrin, Siderophilin

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Do Państwa/SKUDostępnośćCena netto
100 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1310,00 zł
500 mg
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2810,00 zł
1 g
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4830,00 zł

Informacje o tej pozycji

Numer CAS:
UNSPSC Code:
12352202
EC Number:
234-318-8
NACRES:
NA.75
MDL number:
eCl@ss:
34058011
Form:
powder
Assay:
≥98% (agarose gel electrophoresis)
Biological source:
human
Mol wt:
76-81 kDa

1310,00 zł


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biological source

human

Quality Segment

assay

≥98% (agarose gel electrophoresis)

form

powder

mol wt

76-81 kDa

Iron content

≤0.005%

technique(s)

cell culture | mammalian: suitable

impurities

HIV and HBsAg, source material tested negative

solubility

H2O: 50 mg/mL

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TF(7018)

General description

Apo-transferrin human is a glycoprotein, possessing homologous carboxyl and amino domain. Both the domain binds to one molecule of iron. Only 30% of transferrin is saturated with iron in the amino domain. Apo-transferrin in human is encoded by the gene TF which is localized on human chromosome 3q22.1.

Application

Apo-Transferrin human has been used:
  • to determine the competitive binding of bismuth to albumin and transferrin by fast performance liquid chromatography (FPLC)
  • to study titanium-transferrin complex by electrochemical method
  • in the preparation of transferrin solution and in the formation of conjugates with ruthenium-complexes for cellular viability studies

Biochem/physiol Actions

Apo-transferrin is an iron transport protein. The concentration of transferrin in blood plasma is about 35 μM. Transferrin also functions in the transport of therapeutic, diagnostic and toxic ions like Ga3+, Ru3+ and Al3+. Polymorphism in TF gene has pathological implications in Parkinson′s disease.
Apo-transferrin is required for the survival and differentiation of oligodendroglial cells. [1]

Other Notes

Non-heme iron-transport protein.
Similar to T 2252

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Ta pozycja
T2036T5391T1147
biological source

human

biological source

-

biological source

-

biological source

human plasma

assay

≥98% (agarose gel electrophoresis)

assay

≥98% (agarose gel electrophoresis)

assay

≥98%

assay

≥98% (agarose gel electrophoresis)

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

form

powder

form

powder

form

powder

form

powder

mol wt

76-81 kDa

mol wt

76-81 kDa

mol wt

76-81 kDa

mol wt

76-81 kDa

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL


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Klasa składowania

11 - Combustible Solids

wgk

WGK 3



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Questions

1–2 of 2 Questions  
  1. What is the carbohydrate content of human transferrin?

    1 answer
    1. We have found the information on transferrin in a reference book:The Plasma Proteins, F.W. Putnam, ed, volume 2, chapter 4, Table II.According to the table, Transferrin is 6 percent carbohydrate, citing G.A. Jamieson, J. Biol. Chem. 240(7), 2914-2920 (1965).The table also gives information on the percentage of each type of monosaccharide that is present.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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