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S5261

Sodium selenite

BioReagent, suitable for cell culture, ≥98%

Synonim(y):

Selenious acid, Sodium salt

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Gabaryty przesyłkiSKUDostępnośćCena netto
10 g
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
338,00 zł
25 g
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
678,00 zł
100 g
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1350,00 zł

Informacje o tej pozycji

Wzór liniowy:
Na2SeO3
Numer CAS:
Masa cząsteczkowa:
172.94
NACRES:
NA.75
PubChem Substance ID:
UNSPSC Code:
12352205
EC Number:
233-267-9
MDL number:

338,00 zł


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biological source

synthetic (inorganic)

Quality Segment

product line

BioReagent

assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

>350 °C (lit.)

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

[Na+].[Na+].[O-][Se]([O-])=O

InChI

1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2

InChI key

BVTBRVFYZUCAKH-UHFFFAOYSA-L

Application

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.
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Ta pozycja
71950S9133214485
form

powder

form

powder

form

lyophilized powder

form

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

biological source

synthetic (inorganic)

biological source

-

biological source

-

biological source

-

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

-

solubility

-

solubility

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

mp

>350 °C (lit.)

mp

>350 °C (lit.)

mp

>350 °C (lit.)

mp

>350 °C (lit.)


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pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

supp_hazards

Klasa składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Produkty

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.


Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha
Kia A, et al.
Glia, 66(5), 1016-1033 (2018)
Canonical TGF-beta signaling negatively regulates neuronal morphogenesis through TGIF/Smad complex-mediated CRMP2 suppression
Nakashima H, et al.
The Journal of Neuroscience, 2423-2417 (2018)
Miao Zhang et al.
Stem cells (Dayton, Ohio), 33(5), 1456-1469 (2015-02-03)
Directed cardiac differentiation of human pluripotent stem cells (hPSCs) enables disease modeling, investigation of human cardiogenesis, as well as large-scale production of cardiomyocytes (CMs) for translational purposes. Multiple CM differentiation protocols have been developed to individually address specific requirements of



Numer pozycji handlu globalnego

SKUNUMER GTIN
S5261-25G04061835569403
S5261-100G04061835569380
S5261-10G04061835569397

Questions

1–3 of 3 Questions  
  1. need filtration (0.2um) after preparation?

    1 answer
    1. This product is not a sterile preparation. If the intended use, such as in cell culture, requires a sterile environment, then the stock solution would require filter sterilization. Typically, this is achieved by filtration through a 0.22 um membrane. Alternatively, product S9133 is a γ-irradiated, sterile powder. When reconstituted aseptically using sterile water, this product may be added directly to culture medium.
      Please see the link below to review this product option:
      https://www.sigmaaldrich.com/product/sigma/s9133

      Helpful?

  2. How long does an aliquot of this product in water remain stable at -20 degrees Celsius?

    1 answer
    1. As mentioned on the Product Datasheet, stock solutions of sodium selenite may be frozen. Working aliquots remain active for 30 days at 2-8 °C. The Datasheet can accessed in the DOCUMENTATION section under 'More Documents'. Please see the link below:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/245/224/s5261pis.pdf

      Helpful?

  3. What solvent do I need to use? DMSO OK?

    1 answer
    1. This item is soluble in water at 50mg/mL. The solubility in DMSO as not been tested.

      Helpful?

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