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P5234
Purvalanol B
≥97% (HPLC), solid
Synonim(y):
(2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol, NG 95
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1 MG
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About This Item
Wzór empiryczny (zapis Hilla):
C20H25ClN6O3
Numer CAS:
Masa cząsteczkowa:
432.90
Numer MDL:
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
NACRES:
NA.77
380,00 zł
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Polecane produkty
Próba
≥97% (HPLC)
Formularz
solid
rozpuszczalność
DMSO: soluble 37 mg/mL
H2O: insoluble
Warunki transportu
dry ice
temp. przechowywania
−20°C
ciąg SMILES
CC(C)[C@H](CO)Nc1nc(Nc2ccc(C(O)=O)c(Cl)c2)c3ncn(C(C)C)c3n1
InChI
1S/C20H25ClN6O3/c1-10(2)15(8-28)24-20-25-17(16-18(26-20)27(9-22-16)11(3)4)23-12-5-6-13(19(29)30)14(21)7-12/h5-7,9-11,15,28H,8H2,1-4H3,(H,29,30)(H2,23,24,25,26)/t15-/m0/s1
Klucz InChI
ZKDXRFMOHZVXSG-HNNXBMFYSA-N
Działania biochem./fizjol.
Purvalanol B jest zależnym od cyklin inhibitorem 2,6,9-podstawionej kinazy.
Opakowanie
Bottomless glass bottle. Contents are inside inserted fused cone.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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How does the storage temperature relate to shipping conditions?
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The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.
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At what concentration is Product P5234, Purvalanol B, soluble in DMSO?
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We have not necessarily tested a maximum value for solubility of Product P5234, Purvalanol B, in DMSO. However, one publication indicates preparation of a 100 mM stock solution in DMSO. Holton, S., et al., Structures of P. falciparum PfPK5 Test the CDK Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition. Structure, 11(11), 1329-1337 (2003).
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