N183

NBQX disodium salt hydrate

≥98% (HPLC), lyophilized powder, neuroprotective AMPA/kainate glutamate receptor antagonist

• Synonim(y): 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt hydrate, FG 9202 disodium salt hydrate
• Wzór empiryczny (zapis Hilla): C₁₂H₆N₄Na₂O₆S · xH₂O
• Numer CAS: 118876-58-7
• Masa cząsteczkowa: 380.24 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277996
• NACRES: NA.77
• MDL number: MFCD12910445
• Assay: ≥98% (HPLC)
• Form: lyophilized powder
• Quality level: 100
• Storage condition: desiccated

Właściwości

• Nazwa produktu: NBQX disodium salt hydrate, ≥98% (HPLC)
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: lyophilized powder
• storage condition: desiccated
• color: , brown to dark red-brown
• solubility: H₂O: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.[Na+].[Na+].NS(=O)(=O)c1cccc2c1c(cc3nc([O-])c([O-])nc23)[N+]([O-])=O
• InChI: 1S/C12H8N4O6S.2Na.H2O/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6;;;/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22);;;1H2/q;2*+1;/p-2

Opis

Application

NBQX disodium salt hydrate has been used:

• in N-methyl-D-aspartate receptor (NMDAR) kinetic studies
• as an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist for the electrophysiological studies cultured neurons
• in the extracellular solution for current/voltage (I/V) relationship and rectification index experiments in excitatory postsynaptic currents (EPSCs) mediated by NMDA receptors (EPSC_NMDAR)

Biochem/physiol Actions

NBQX disodium salt hydrate is a neuroprotective AMPA/kainate glutamate receptor antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves