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M9697

MST1, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonim(y):

DKFZp686A2068, KRS2, STK4, YSK3

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Gabaryty przesyłkiSKUDostępnośćCena netto
10 μg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
2100,00 zł

Informacje o tej pozycji

NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
952-1288 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

2100,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
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Pozwól nam pomóc

recombinant

expressed in baculovirus infected Sf9 cells

Quality Level

200

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

952-1288 nmol/min·mg

mol wt

~83 kDa

UniProt accession no.

Q13043

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... STK4(6789)

Biochem/physiol Actions

MST1 belongs to a family of proteins that share similarity with a budding yeast serine/threonine kinase, sterile-20 (Ste20). Endogenous full-length MST1 is activated by a variety of stressful stimuli, accompanied by the secondary appearance of a 36 kDa Thr183-phosphorylated, caspase-cleaved catalytic fragment. Recombinant MST1 undergoes a robust autoactivation in vitro, mediated by an intramolecular autophosphorylation on the activation loop of an MST dimer. MST1 can initiate apoptosis when transiently overexpressed in mammalian cells. Interference with the ability of endogenous MST1 to associate with the putative tumor suppressor proteins Nore1/RASSF can inhibit Ras-induced apoptosis.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
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Ta pozycja
WH0006789M1K3018M8822
MST1, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

M9697

MST1, active, GST tagged human

Monoclonal Anti-STK4 antibody produced in mouse clone 1D7-8A10, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

WH0006789M1

Monoclonal Anti-STK4 antibody produced in mouse

PAK3, active, GST tagged from mouse PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

K3018

PAK3, active, GST tagged from mouse

MEK1, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

M8822

MEK1, active, GST tagged human

assay

≥70% (SDS-PAGE)

assay

-

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

specific activity

952-1288 nmol/min·mg

specific activity

-

specific activity

221-298 nmol/min·mg

specific activity

276-374 nmol/min·mg

Gene Information

human ... STK4(6789)

Gene Information

human ... STK4(6789)

Gene Information

mouse ... Pak3(18481)

Gene Information

human ... Map2k1(26395)

form

buffered aqueous glycerol solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

-

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−70°C

storage temp.

−70°C

Klasa składowania

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number
SLBL7616V
SLBJ4985V
SLBJ5354V
SLBJ6097V
SLBG0926V

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Joseph Avruch et al.
Methods in enzymology, 407, 290-310 (2006-06-08)
The six human Nore1/RASSF genes encode a family of putative tumor suppressor proteins, each expressed as multiple mRNA splice variants. The predominant isoforms of these noncatalytic polypeptides are characterized by the presence in their carboxyterminal segments of a Ras-Association (RA)
P M de Souza et al.
Biochemical Society transactions, 32(Pt3), 485-488 (2004-05-26)
Mammalian Sterile20-like kinase 1 (Mst1) is a ubiquitously expressed serine/threonine kinase which represents a member of the rapidly expanding family of enzymes related to the yeast Sterile20 kinase. Although the physiological function of Mst1 and its role in intracellular signalling
Yavuz Kulaberoglu et al.
Nature communications, 8(1), 695-695 (2017-09-28)
The Hippo tumor suppressor pathway is essential for development and tissue growth control, encompassing a core cassette consisting of the Hippo (MST1/2), Warts (LATS1/2), and Tricornered (NDR1/2) kinases together with MOB1 as an important signaling adaptor. However, it remains unclear

Numer pozycji handlu globalnego

SKUNUMER GTIN
M9697-10UG04061837756139

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