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F8055

FGR, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonim(y):

SRC2, c-fgr, p55c-fgr

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Gabaryty przesyłkiSKUDostępnośćCena netto
10 μg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1920,00 zł
1632,00 zł

Informacje o tej pozycji

NACRES:
NA.32
UNSPSC Code:
51111800

1632,00 zł

Cena katalogowa1920,00 złZaoszczędź 15%
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
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Pozwól nam pomóc

recombinant

expressed in baculovirus infected Sf9 cells

Quality Level

200

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

242-328 nmol/min·mg

mol wt

~86 kDa

UniProt accession no.

P09769

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... FGR(2268)

General description

Src family of tyrosine kinases is grouped into two classes- those with wide range of expression, and those with narrow range of tissue expression. Fgr belongs to the latter group. This protein has six functional domains namely, Src homology domain 4 (SH4), a unique domain, SH3 domain, SH2 domain, the catalytic SH1 domain, and a regulatory region in C-terminal.[1] It is expressed in natural killer cells, monocytes and granulocytes.[2]

Biochem/physiol Actions

FGR interacts with Fc?RII and thus, regulates Fc?RII-mediated signaling cascade.
This protein is expressed in B-cells of patients with Epstein-Barr virus-associated lymphoproliferative disease and chronic lymphocytic leukemia. It is also expressed in normal mantle zone B-cells and is controlled developmentally during the differentiation of myelomonocytes.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
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Ta pozycja
F7930F6432SRP5084
FGR, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

F8055

FGR, active, GST tagged human

FGFR3 (397-end), active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

F7930

FGFR3 (397-end), active, GST tagged human

FLT3 (571-993), active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

F6432

FLT3 (571-993), active, GST tagged human

ROS1 (1883-end), active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5084

ROS1 (1883-end), active, GST tagged human

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

mol wt

~86 kDa

mol wt

~73 kDa

mol wt

~73 kDa

mol wt

~82 kDa

UniProt accession no.

P09769

UniProt accession no.

P22607

UniProt accession no.

P36888

UniProt accession no.

-

Klasa składowania

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number
SLBX9423
SLBN8504V
SLBJ4986V

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Powiązane treści

C L Willman et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(13), 4480-4484 (1987-07-01)
To study the expression of src-related protooncogenes during the development of myeloid cells and the regulation of these genes by the colony-stimulating factors that control myelopoiesis, normal monocytic cells at distinct stages of differentiation were derived from murine bone marrow
M S Cheah et al.
Nature, 319(6050), 238-240 (1986-01-16)
Several acute transforming retroviruses encode tyrosine-specific protein kinases which possess structural and functional relationships to cell-surface receptors for certain growth factors. One such tyrosine kinase is encoded by the onc gene, v-fgr, of Gardner-Rasheed feline sarcoma virus (GR-FeSV). Recently, we
F Hamada et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(13), 6305-6309 (1993-07-01)
The interaction of Fc receptors with antibody-antigen complexes activates multiple biological functions in hematopoietic cells. Recently, protein-tyrosine phosphorylation has been suggested to be involved in Fc receptor-mediated cell signaling. Here we show that the Src-like protein-tyrosine kinase Fgr, which is
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SKUNUMER GTIN
F8055-10UG04061837753718

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