D8946

DMH1

≥98% (HPLC), powder, BMP inhibitor

• Synonim(y): 4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
• Wzór empiryczny (zapis Hilla): C₂₄H₂₀N₄O
• Numer CAS: 1206711-16-1
• Masa cząsteczkowa: 380.44
• UNSPSC Code: 51111800
• PubChem Substance ID: 329798883
• NACRES: NA.77
• MDL number: MFCD18384963
• Assay: ≥98% (HPLC)
• Form: powder
• Quality level: 100
• Storage condition: desiccated

Właściwości

• Nazwa produktu: DMH1, ≥98% (HPLC)
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: light yellow to orange
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: CC(C)OC(C=C1)=CC=C1C(C=N2)=CN3C2=C(C4=CC=NC5=C4C=CC=C5)C=N3
• InChI: 1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
• InChI key: JMIFGARJSWXZSH-UHFFFAOYSA-N

Opis

General description

DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses.

Application

DMH1 has been used for bone morphogenetic protein (BMP) inhibition.

Biochem/physiol Actions

DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor.

DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH1 is a dorsomorphin analogue that exclusively targets the BMP but not the VEGF pathway.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable